Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status.

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Title: Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status.
Authors: Suzuki S; a First Department of Medicine , Hamamatsu University School of Medicine , Hamamatsu , Shizuoka , Japan., Iwaizumi M; a First Department of Medicine , Hamamatsu University School of Medicine , Hamamatsu , Shizuoka , Japan.; b Division of Gastroenterology, Department of Internal Medicine and Department of Human Genetics, University of Michigan , Ann Arbor , MA , USA., Tseng-Rogenski S; b Division of Gastroenterology, Department of Internal Medicine and Department of Human Genetics, University of Michigan , Ann Arbor , MA , USA., Hamaya Y; a First Department of Medicine , Hamamatsu University School of Medicine , Hamamatsu , Shizuoka , Japan.; b Division of Gastroenterology, Department of Internal Medicine and Department of Human Genetics, University of Michigan , Ann Arbor , MA , USA., Miyajima H; a First Department of Medicine , Hamamatsu University School of Medicine , Hamamatsu , Shizuoka , Japan., Kanaoka S; c Department of Gastroenterology , Hamamatsu Medical Center , Shizuoka , Japan., Sugimoto K; a First Department of Medicine , Hamamatsu University School of Medicine , Hamamatsu , Shizuoka , Japan., Carethers JM; b Division of Gastroenterology, Department of Internal Medicine and Department of Human Genetics, University of Michigan , Ann Arbor , MA , USA.
Source: Cancer biology & therapy [Cancer Biol Ther] 2016 Jul 02; Vol. 17 (7), pp. 760-8. Date of Electronic Publication: 2016 Apr 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1555-8576
DOI:10.1080/15384047.2016.1178430