A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.
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| Title: | A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors. |
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| Authors: | Blevitt JM; Discovery Sciences, Janssen Research and Development, San Diego, California 92121., Hack MD; Discovery Sciences, Janssen Research and Development, San Diego, California 92121., Herman K; Discovery Sciences, Janssen Research and Development, San Diego, California 92121., Chang L; From the Departments of Immunology and., Keith JM; From the Departments of Immunology and., Mirzadegan T; Discovery Sciences, Janssen Research and Development, San Diego, California 92121., Rao NL; From the Departments of Immunology and., Lebsack AD; From the Departments of Immunology and., Milla ME; Discovery Sciences, Janssen Research and Development, San Diego, California 92121. Electronic address: mmilla@adaptivebiotech.com. |
| Source: | The Journal of biological chemistry [J Biol Chem] 2016 Jun 10; Vol. 291 (24), pp. 12724-12731. Date of Electronic Publication: 2016 Apr 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 27129215 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Blevitt+JM%22">Blevitt JM</searchLink>; Discovery Sciences, Janssen Research and Development, San Diego, California 92121.<br /><searchLink fieldCode="AU" term="%22Hack+MD%22">Hack MD</searchLink>; Discovery Sciences, Janssen Research and Development, San Diego, California 92121.<br /><searchLink fieldCode="AU" term="%22Herman+K%22">Herman K</searchLink>; Discovery Sciences, Janssen Research and Development, San Diego, California 92121.<br /><searchLink fieldCode="AU" term="%22Chang+L%22">Chang L</searchLink>; From the Departments of Immunology and.<br /><searchLink fieldCode="AU" term="%22Keith+JM%22">Keith JM</searchLink>; From the Departments of Immunology and.<br /><searchLink fieldCode="AU" term="%22Mirzadegan+T%22">Mirzadegan T</searchLink>; Discovery Sciences, Janssen Research and Development, San Diego, California 92121.<br /><searchLink fieldCode="AU" term="%22Rao+NL%22">Rao NL</searchLink>; From the Departments of Immunology and.<br /><searchLink fieldCode="AU" term="%22Lebsack+AD%22">Lebsack AD</searchLink>; From the Departments of Immunology and.<br /><searchLink fieldCode="AU" term="%22Milla+ME%22">Milla ME</searchLink>; Discovery Sciences, Janssen Research and Development, San Diego, California 92121. Electronic address: mmilla@adaptivebiotech.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2016 Jun 10; Vol. 291 (24), pp. 12724-12731. <i>Date of Electronic Publication: </i>2016 Apr 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=27129215 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1074/jbc.M116.725325 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 12724 Titles: – TitleFull: A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Blevitt JM – PersonEntity: Name: NameFull: Hack MD – PersonEntity: Name: NameFull: Herman K – PersonEntity: Name: NameFull: Chang L – PersonEntity: Name: NameFull: Keith JM – PersonEntity: Name: NameFull: Mirzadegan T – PersonEntity: Name: NameFull: Rao NL – PersonEntity: Name: NameFull: Lebsack AD – PersonEntity: Name: NameFull: Milla ME IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 06 Text: 2016 Jun 10 Type: published Y: 2016 Identifiers: – Type: issn-electronic Value: 1083-351X Numbering: – Type: volume Value: 291 – Type: issue Value: 24 Titles: – TitleFull: The Journal of biological chemistry Type: main |
| ResultId | 1 |
