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Effects of Single Low Dose of Dexamethasone before Noncardiac and Nonneurologic Surgery and General Anesthesia on Postoperative Cognitive Dysfunction-A Phase III Double Blind, Randomized Clinical Trial.

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Title: Effects of Single Low Dose of Dexamethasone before Noncardiac and Nonneurologic Surgery and General Anesthesia on Postoperative Cognitive Dysfunction-A Phase III Double Blind, Randomized Clinical Trial.
Authors: Valentin LS; Department of Anesthesia, LIM 8 -Laboratory of Anesthesiology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil., Pereira VF; Department of Anesthesia, LIM 8 -Laboratory of Anesthesiology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil., Pietrobon RS; Department of Surgery, Duke University Health System, Durham, North Carolina, United States of America., Schmidt AP; Department of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Department of Anesthesia and Perioperative Medicine, Hospital de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil., Oses JP; Center of Sciences of the Life and Health, Universidade Católica de Pelotas, Pelotas, Rio Grande do Sul, Brazil., Portela LV; Department of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Souza DO; Department of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Vissoci JR; Department of Surgery, Duke University Health System, Durham, North Carolina, United States of America., Luz VF; Department of Anesthesia, LIM 8 -Laboratory of Anesthesiology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil., Trintoni LM; Department of Anesthesia, LIM 8 -Laboratory of Anesthesiology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil., Nielsen KC; Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, United States of America., Carmona MJ; Department of Anesthesia, LIM 8 -Laboratory of Anesthesiology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Source: PloS one [PLoS One] 2016 May 06; Vol. 11 (5), pp. e0152308. Date of Electronic Publication: 2016 May 06 (Print Publication: 2016).
Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-6203
DOI:10.1371/journal.pone.0152308