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Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

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Title: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.
Authors: Chabon JJ; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA., Simmons AD; Clovis Oncology, Inc., San Francisco, California 94158, USA., Lovejoy AF; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA., Esfahani MS; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA., Newman AM; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA., Haringsma HJ; Clovis Oncology, Inc., San Francisco, California 94158, USA., Kurtz DM; Division of Oncology, Department of Medicine, Stanford University, Stanford, California 94305, USA.; Department of Bioengineering, Stanford University, Stanford, California 94305, USA., Stehr H; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA., Scherer F; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA.; Division of Oncology, Department of Medicine, Stanford University, Stanford, California 94305, USA., Karlovich CA; Clovis Oncology, Inc., San Francisco, California 94158, USA., Harding TC; Clovis Oncology, Inc., San Francisco, California 94158, USA., Durkin KA; Molecular Graphics and Computation Facility, College of Chemistry, University of California, Berkeley, California 94720, USA., Otterson GA; The Ohio State University, Columbus, Ohio 43210, USA., Purcell WT; Division of Medical Oncology, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado 80045, USA., Camidge DR; Division of Medical Oncology, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado 80045, USA., Goldman JW; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA., Sequist LV; Massachusetts General Hospital &Harvard Medical School, Boston, Massachusetts 02115, USA., Piotrowska Z; Massachusetts General Hospital &Harvard Medical School, Boston, Massachusetts 02115, USA., Wakelee HA; Division of Oncology, Department of Medicine, Stanford University, Stanford, California 94305, USA., Neal JW; Division of Oncology, Department of Medicine, Stanford University, Stanford, California 94305, USA., Alizadeh AA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA.; Division of Oncology, Department of Medicine, Stanford University, Stanford, California 94305, USA.; Division of Hematology, Department of Medicine, Stanford University, Stanford, California 94305, USA., Diehn M; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California 94305, USA.; Stanford Cancer Institute, Stanford University, Stanford, California 94305, USA.; Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA.
Source: Nature communications [Nat Commun] 2016 Jun 10; Vol. 7, pp. 11815. Date of Electronic Publication: 2016 Jun 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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