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Unique safety issues associated with virus-vectored vaccines: Potential for and theoretical consequences of recombination with wild type virus strains.

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Title: Unique safety issues associated with virus-vectored vaccines: Potential for and theoretical consequences of recombination with wild type virus strains.
Authors: Condit RC; Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, USA., Williamson AL; Institute of Infectious Disease and Molecular Medicine, University of Cape Town and National Health Laboratory Service, Cape Town, South Africa., Sheets R; Independent Adviser (formerly of NIAID, NIH, Bethesda, MD 20893, USA)., Seligman SJ; Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, NY 10065, USA., Monath TP; Kleiner Perkins Caufield & Byers, Menlo Park, CA 94025, USA., Excler JL; US Military HIV Research Program (MHRP), Bethesda, MD 20817, USA (formerly of International AIDS Vaccine Initiative, New York, NY 10004, USA)., Gurwith M; PaxVax Inc., 900 Veterans Boulevard, Ste 500, San Diego, CA 92121, USA., Bok K; National Vaccine Program Office, Office of the Assistant Secretary for Health (OASH), U.S. Department of Health and Human Services, Washington, DC 20201, USA., Robertson JS; Independent Adviser (formerly of National Institute for Biological Standards and Control, Potters Bar, EN6 3QG, UK)., Kim D; Takeda Vaccines, Inc., One Takeda Parkway, Deerfield, IL 60015, USA., Michael Hendry R; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA., Singh V; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA. Electronic address: brightoncollaborationv3swg@gmail.com., Mac LM; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA., Chen RT; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
Corporate Authors: Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG)
Source: Vaccine [Vaccine] 2016 Dec 12; Vol. 34 (51), pp. 6610-6616. Date of Electronic Publication: 2016 Jun 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Condit+RC%22">Condit RC</searchLink>; Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Williamson+AL%22">Williamson AL</searchLink>; Institute of Infectious Disease and Molecular Medicine, University of Cape Town and National Health Laboratory Service, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Sheets+R%22">Sheets R</searchLink>; Independent Adviser (formerly of NIAID, NIH, Bethesda, MD 20893, USA).<br /><searchLink fieldCode="AU" term="%22Seligman+SJ%22">Seligman SJ</searchLink>; Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA; St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Monath+TP%22">Monath TP</searchLink>; Kleiner Perkins Caufield & Byers, Menlo Park, CA 94025, USA.<br /><searchLink fieldCode="AU" term="%22Excler+JL%22">Excler JL</searchLink>; US Military HIV Research Program (MHRP), Bethesda, MD 20817, USA (formerly of International AIDS Vaccine Initiative, New York, NY 10004, USA).<br /><searchLink fieldCode="AU" term="%22Gurwith+M%22">Gurwith M</searchLink>; PaxVax Inc., 900 Veterans Boulevard, Ste 500, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Bok+K%22">Bok K</searchLink>; National Vaccine Program Office, Office of the Assistant Secretary for Health (OASH), U.S. Department of Health and Human Services, Washington, DC 20201, USA.<br /><searchLink fieldCode="AU" term="%22Robertson+JS%22">Robertson JS</searchLink>; Independent Adviser (formerly of National Institute for Biological Standards and Control, Potters Bar, EN6 3QG, UK).<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Takeda Vaccines, Inc., One Takeda Parkway, Deerfield, IL 60015, USA.<br /><searchLink fieldCode="AU" term="%22Michael+Hendry+R%22">Michael Hendry R</searchLink>; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.<br /><searchLink fieldCode="AU" term="%22Singh+V%22">Singh V</searchLink>; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA. Electronic address: brightoncollaborationv3swg@gmail.com.<br /><searchLink fieldCode="AU" term="%22Mac+LM%22">Mac LM</searchLink>; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.<br /><searchLink fieldCode="AU" term="%22Chen+RT%22">Chen RT</searchLink>; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
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  Data: <searchLink fieldCode="CA" term="%22Brighton+Collaboration+Viral+Vector+Vaccines+Safety+Working+Group+%28V3SWG%29%22">Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG)</searchLink>
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  Data: <searchLink fieldCode="JN" term="%228406899%22">Vaccine</searchLink> [Vaccine] 2016 Dec 12; Vol. 34 (51), pp. 6610-6616. <i>Date of Electronic Publication: </i>2016 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8406899 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2518 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220264410X%22">0264410X </searchLink><i>NLM ISO Abbreviation: </i>Vaccine <i>Subsets: </i>MEDLINE
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