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A multi-centred randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer.

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Title: A multi-centred randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer.
Authors: Borstlap WA; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Tanis PJ; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Koedam TW; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HZ, Amsterdam, The Netherlands., Marijnen CA; Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands., Cunningham C; Department of Surgery, Oxford University Hospital, Oxford, UK., Dekker E; Department of Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., van Leerdam ME; Department of Gastroenterology, Antoni Van Leeuwenhoek, Amsterdam, The Netherlands., Meijer G; Department of Pathology, Antoni Van Leeuwenhoek, Amsterdam, The Netherlands., van Grieken N; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands., Nagtegaal ID; Department of Pathology, RadboudUMC, Nijmegen, The Netherlands., Punt CJ; Department of Medical Oncology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Dijkgraaf MG; Clinical Research Unit, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., De Wilt JH; Department of Surgery, RadboudUMC, Nijmegen, The Netherlands., Beets G; Department of Surgery, Antoni van Leeuwenhoek, Amsterdam, The Netherlands., de Graaf EJ; Department of Surgery, IJselland Hospital, Capelle aan de Ijssel, The Netherlands., van Geloven AA; Department of surgery, Tergooi Hospital, Hilversum, The Netherlands., Gerhards MF; Department of surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands., van Westreenen HL; Department of surgery, Isala Hospital, Zwolle, The Netherlands., van de Ven AW; Department of surgery, Flevo Hospital, Almere, The Netherlands., van Duijvendijk P; Department of surgery, Gelre Hospital, Apeldoorn, The Netherlands., de Hingh IH; Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands., Leijtens JW; Department of Surgery, Laurentius Hospital, Roermond, The Netherlands., Sietses C; Department of Surgery, Gelderse Vallei Hospital, Ede, The Netherlands., Spillenaar-Bilgen EJ; Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands., Vuylsteke RJ; Department of Surgery, Spaarne Gasthuis, Haarlem, The Netherlands., Hoff C; Department of Surgery, Medisch Centrum Leewarden, Leeuwarden, The Netherlands., Burger JW; Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands., van Grevenstein WM; Department of Surgery, University Medical Center, Utrecht, The Netherlands., Pronk A; Department of Surgery, Diaconessenziekehuis, Utrecht, The Netherlands., Bosker RJ; Department of Surgery, Deventer Hospital, Deventer, The Netherlands., Prins H; Department of Surgery, Jeroen Bosch Hospital, Den Bosch, The Netherlands., Smits AB; Department of Surgery, Sint. Antonius Hospital, Nieuwegein, The Netherlands., Bruin S; Department of Surgery, Slotervaart Hospital, Amsterdam, The Netherlands., Zimmerman DD; Department of Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands., Stassen LP; Department of Surgery, MUMC, Maastricht, The Netherlands., Dunker MS; Department of Surgery, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands., Westerterp M; Department of Surgery, Medical Center Haaglanden, The Hague, The Netherlands., Coene PP; Department of Surgery, Maasstad Hospital, Rotterdam, The Netherlands., Stoot J; Department of Surgery, Zuyderland Hospital, Sittard, The Netherlands., Bemelman WA; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Tuynman JB; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HZ, Amsterdam, The Netherlands. j.tuynman@vumc.nl.
Source: BMC cancer [BMC Cancer] 2016 Jul 21; Vol. 16, pp. 513. Date of Electronic Publication: 2016 Jul 21.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A multi-centred randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Borstlap+WA%22">Borstlap WA</searchLink>; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tanis+PJ%22">Tanis PJ</searchLink>; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koedam+TW%22">Koedam TW</searchLink>; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Marijnen+CA%22">Marijnen CA</searchLink>; Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cunningham+C%22">Cunningham C</searchLink>; Department of Surgery, Oxford University Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dekker+E%22">Dekker E</searchLink>; Department of Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Leerdam+ME%22">van Leerdam ME</searchLink>; Department of Gastroenterology, Antoni Van Leeuwenhoek, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Meijer+G%22">Meijer G</searchLink>; Department of Pathology, Antoni Van Leeuwenhoek, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Grieken+N%22">van Grieken N</searchLink>; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nagtegaal+ID%22">Nagtegaal ID</searchLink>; Department of Pathology, RadboudUMC, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Punt+CJ%22">Punt CJ</searchLink>; Department of Medical Oncology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijkgraaf+MG%22">Dijkgraaf MG</searchLink>; Clinical Research Unit, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22De+Wilt+JH%22">De Wilt JH</searchLink>; 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Department of surgery, Gelre Hospital, Apeldoorn, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Hingh+IH%22">de Hingh IH</searchLink>; Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Leijtens+JW%22">Leijtens JW</searchLink>; Department of Surgery, Laurentius Hospital, Roermond, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sietses+C%22">Sietses C</searchLink>; Department of Surgery, Gelderse Vallei Hospital, Ede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Spillenaar-Bilgen+EJ%22">Spillenaar-Bilgen EJ</searchLink>; Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vuylsteke+RJ%22">Vuylsteke RJ</searchLink>; Department of Surgery, Spaarne Gasthuis, Haarlem, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hoff+C%22">Hoff C</searchLink>; Department of Surgery, Medisch Centrum Leewarden, Leeuwarden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+JW%22">Burger JW</searchLink>; Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Grevenstein+WM%22">van Grevenstein WM</searchLink>; Department of Surgery, University Medical Center, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pronk+A%22">Pronk A</searchLink>; Department of Surgery, Diaconessenziekehuis, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bosker+RJ%22">Bosker RJ</searchLink>; Department of Surgery, Deventer Hospital, Deventer, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Prins+H%22">Prins H</searchLink>; Department of Surgery, Jeroen Bosch Hospital, Den Bosch, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smits+AB%22">Smits AB</searchLink>; Department of Surgery, Sint. Antonius Hospital, Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bruin+S%22">Bruin S</searchLink>; Department of Surgery, Slotervaart Hospital, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zimmerman+DD%22">Zimmerman DD</searchLink>; Department of Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stassen+LP%22">Stassen LP</searchLink>; Department of Surgery, MUMC, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dunker+MS%22">Dunker MS</searchLink>; Department of Surgery, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Westerterp+M%22">Westerterp M</searchLink>; Department of Surgery, Medical Center Haaglanden, The Hague, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Coene+PP%22">Coene PP</searchLink>; Department of Surgery, Maasstad Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stoot+J%22">Stoot J</searchLink>; Department of Surgery, Zuyderland Hospital, Sittard, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bemelman+WA%22">Bemelman WA</searchLink>; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tuynman+JB%22">Tuynman JB</searchLink>; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HZ, Amsterdam, The Netherlands. j.tuynman@vumc.nl.
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  Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2016 Jul 21; Vol. 16, pp. 513. <i>Date of Electronic Publication: </i>2016 Jul 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE
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