Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.
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| Title: | Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. |
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| Authors: | Vogl C; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany., Panou I; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Göttingen Graduate School for Neurosciences, Biophysics and Molecular Biosciences, University of Göttingen, Göttingen, Germany., Yamanbaeva G; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Auditory Systems Physiology Group and InnerEarLab, Department of Otolaryngology, University of Göttingen Medical Center, Göttingen, Germany., Wichmann C; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Molecular Architecture of Synapses Group, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany., Mangosing SJ; Otolaryngology Division, Department of Surgery, School of Medicine, University of California San Diego, La Jolla, CA, USA., Vilardi F; Institute of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany., Indzhykulian AA; Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Pangršič T; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Synaptic Physiology of Mammalian Vestibular Hair Cells Junior Research Group, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany., Santarelli R; Department of Neurosciences, University of Padova, Padova, Italy.; Audiology and Phoniatrics Service, Treviso Regional Hospital, Treviso, Italy., Rodriguez-Ballesteros M; Servicio de Genetica, Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain., Weber T; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany., Jung S; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.; Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Cardenas E; Otolaryngology Division, Department of Surgery, School of Medicine, University of California San Diego, La Jolla, CA, USA., Wu X; Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Wojcik SM; Department of Molecular Neurobiology, Max-Planck-Institute for Experimental Medicine, Göttingen, Germany., Kwan KY; W. M. Keck Center for Collaborative Neuroscience, Nelson Lab-D250, Rutgers University, Piscataway, NJ, USA., Del Castillo I; Servicio de Genetica, Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain.; Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER), Madrid, Spain., Schwappach B; Institute of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany., Strenzke N; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Auditory Systems Physiology Group and InnerEarLab, Department of Otolaryngology, University of Göttingen Medical Center, Göttingen, Germany., Corey DP; Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, Boston, MA, USA david_corey@hms.harvard.edu shuh-yow@ucsd.edu tmoser@gwdg.de., Lin SY; Otolaryngology Division, Department of Surgery, School of Medicine, University of California San Diego, La Jolla, CA, USA david_corey@hms.harvard.edu shuh-yow@ucsd.edu tmoser@gwdg.de., Moser T; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany david_corey@hms.harvard.edu shuh-yow@ucsd.edu tmoser@gwdg.de.; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Center for Nanoscale Microscopy and Molecular Physiology of the Brain, University Medical Center Göttingen, Göttingen, Germany. |
| Source: | The EMBO journal [EMBO J] 2016 Dec 01; Vol. 35 (23), pp. 2536-2552. Date of Electronic Publication: 2016 Jul 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 27458190 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Vogl+C%22">Vogl C</searchLink>; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Panou+I%22">Panou I</searchLink>; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Göttingen Graduate School for Neurosciences, Biophysics and Molecular Biosciences, University of Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Yamanbaeva+G%22">Yamanbaeva G</searchLink>; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Auditory Systems Physiology Group and InnerEarLab, Department of Otolaryngology, University of Göttingen Medical Center, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wichmann+C%22">Wichmann C</searchLink>; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Molecular Architecture of Synapses Group, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Mangosing+SJ%22">Mangosing SJ</searchLink>; Otolaryngology Division, Department of Surgery, School of Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vilardi+F%22">Vilardi F</searchLink>; Institute of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Indzhykulian+AA%22">Indzhykulian AA</searchLink>; Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pangršič+T%22">Pangršič T</searchLink>; Collaborative Research Center 889, University of Göttingen, Göttingen, Germany.; Synaptic Physiology of Mammalian Vestibular Hair Cells Junior Research Group, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Santarelli+R%22">Santarelli R</searchLink>; Department of Neurosciences, University of Padova, Padova, Italy.; Audiology and Phoniatrics Service, Treviso Regional Hospital, Treviso, Italy.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Ballesteros+M%22">Rodriguez-Ballesteros M</searchLink>; Servicio de Genetica, Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Weber+T%22">Weber T</searchLink>; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jung+S%22">Jung S</searchLink>; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany.; Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Cardenas+E%22">Cardenas E</searchLink>; Otolaryngology Division, Department of Surgery, School of Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Howard Hughes Medical Institute and Department of Neurobiology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wojcik+SM%22">Wojcik SM</searchLink>; Department of Molecular Neurobiology, Max-Planck-Institute for Experimental Medicine, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kwan+KY%22">Kwan KY</searchLink>; W. 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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.15252/embj.201593565 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2536 Titles: – TitleFull: Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Vogl C – PersonEntity: Name: NameFull: Panou I – PersonEntity: Name: NameFull: Yamanbaeva G – PersonEntity: Name: NameFull: Wichmann C – PersonEntity: Name: NameFull: Mangosing SJ – PersonEntity: Name: NameFull: Vilardi F – PersonEntity: Name: NameFull: Indzhykulian AA – PersonEntity: Name: NameFull: Pangršič T – PersonEntity: Name: NameFull: Santarelli R – PersonEntity: Name: NameFull: Rodriguez-Ballesteros M – PersonEntity: Name: NameFull: Weber T – PersonEntity: Name: NameFull: Jung S – PersonEntity: Name: NameFull: Cardenas E – PersonEntity: Name: NameFull: Wu X – PersonEntity: Name: NameFull: Wojcik SM – PersonEntity: Name: NameFull: Kwan KY – PersonEntity: Name: NameFull: Del Castillo I – PersonEntity: Name: NameFull: Schwappach B – PersonEntity: Name: NameFull: Strenzke N – PersonEntity: Name: NameFull: Corey DP – PersonEntity: Name: NameFull: Lin SY – PersonEntity: Name: NameFull: Moser T IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2016 Dec 01 Type: published Y: 2016 Identifiers: – Type: issn-electronic Value: 1460-2075 Numbering: – Type: volume Value: 35 – Type: issue Value: 23 Titles: – TitleFull: The EMBO journal Type: main |
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