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Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKCδ Signaling Axis.

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Title: Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKCδ Signaling Axis.
Authors: Shapiro BA; From the Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia 23249.; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614., Vu NT; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614., Shultz MD; From the Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia 23249., Shultz JC; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614., Mietla JA; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614., Gouda MM; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614., Yacoub A; the Department of Neurosurgery, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614., Dent P; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.; the Virginia Commonwealth University Institute of Molecular Medicine, Richmond, Virginia 23298.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and., Fisher PB; the Virginia Commonwealth University Institute of Molecular Medicine, Richmond, Virginia 23298, paul.fisher@vcuhealth.org.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and.; the Department of Human and Molecular Genetics, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298., Park MA; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614, margaret.park@vcuhealth.org.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and., Chalfant CE; From the Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia 23249, charles.chalfant@vcuhealth.org.; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.; the Virginia Commonwealth University Institute of Molecular Medicine, Richmond, Virginia 23298.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and.; the Virginia Commonwealth University Johnson Center for Critical Care and Pulmonary Research, Richmond, Virginia 23298.
Source: The Journal of biological chemistry [J Biol Chem] 2016 Oct 07; Vol. 291 (41), pp. 21669-21681. Date of Electronic Publication: 2016 Aug 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
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  Data: Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKCδ Signaling Axis.
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  Data: <searchLink fieldCode="AU" term="%22Shapiro+BA%22">Shapiro BA</searchLink>; From the Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia 23249.; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.<br /><searchLink fieldCode="AU" term="%22Vu+NT%22">Vu NT</searchLink>; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.<br /><searchLink fieldCode="AU" term="%22Shultz+MD%22">Shultz MD</searchLink>; From the Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia 23249.<br /><searchLink fieldCode="AU" term="%22Shultz+JC%22">Shultz JC</searchLink>; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.<br /><searchLink fieldCode="AU" term="%22Mietla+JA%22">Mietla JA</searchLink>; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.<br /><searchLink fieldCode="AU" term="%22Gouda+MM%22">Gouda MM</searchLink>; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.<br /><searchLink fieldCode="AU" term="%22Yacoub+A%22">Yacoub A</searchLink>; the Department of Neurosurgery, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.<br /><searchLink fieldCode="AU" term="%22Dent+P%22">Dent P</searchLink>; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.; the Virginia Commonwealth University Institute of Molecular Medicine, Richmond, Virginia 23298.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and.<br /><searchLink fieldCode="AU" term="%22Fisher+PB%22">Fisher PB</searchLink>; the Virginia Commonwealth University Institute of Molecular Medicine, Richmond, Virginia 23298, paul.fisher@vcuhealth.org.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and.; the Department of Human and Molecular Genetics, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298.<br /><searchLink fieldCode="AU" term="%22Park+MA%22">Park MA</searchLink>; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614, margaret.park@vcuhealth.org.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and.<br /><searchLink fieldCode="AU" term="%22Chalfant+CE%22">Chalfant CE</searchLink>; From the Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, Virginia 23249, charles.chalfant@vcuhealth.org.; the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University-School of Medicine, Richmond, Virginia 23298-0614.; the Virginia Commonwealth University Institute of Molecular Medicine, Richmond, Virginia 23298.; the Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia 23298, and.; the Virginia Commonwealth University Johnson Center for Critical Care and Pulmonary Research, Richmond, Virginia 23298.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2016 Oct 07; Vol. 291 (41), pp. 21669-21681. <i>Date of Electronic Publication: </i>2016 Aug 12.
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