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Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.

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Title: Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
Authors: Carrasco MP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal. marta.carrasco@chem.gu.se.; Department of Chemistry and Molecular Biology, University of Gothenburg, 412 96, Göteborg, Sweden. marta.carrasco@chem.gu.se., Machado M; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal., Gonçalves L; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal., Sharma M; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal., Gut J; Department of Medicine, San Francisco General Hospital, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA, 94110, USA., Lukens AK; The Broad Institute, Infectious Diseases Program, Cambridge, MA, 02142, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Wirth DF; The Broad Institute, Infectious Diseases Program, Cambridge, MA, 02142, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., André V; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, 1049-001, Lisboa, Portugal., Duarte MT; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, 1049-001, Lisboa, Portugal., Guedes RC; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal., Dos Santos DJ; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.; LAQV@REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal., Rosenthal PJ; Department of Medicine, San Francisco General Hospital, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA, 94110, USA., Mazitschek R; The Broad Institute, Infectious Diseases Program, Cambridge, MA, 02142, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Center for System Biology, Massachusetts General Hospital and Harvard Medical School, Richard B. Simches Research Center, 185 Cambridge Street, Boston, MA, 02114, USA., Prudêncio M; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal. mprudencio@medicina.ulisboa.pt., Moreira R; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
Source: ChemMedChem [ChemMedChem] 2016 Oct 06; Vol. 11 (19), pp. 2194-2204. Date of Electronic Publication: 2016 Aug 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
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  Data: Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
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  Data: <searchLink fieldCode="AU" term="%22Carrasco+MP%22">Carrasco MP</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal. marta.carrasco@chem.gu.se.; Department of Chemistry and Molecular Biology, University of Gothenburg, 412 96, Göteborg, Sweden. marta.carrasco@chem.gu.se.<br /><searchLink fieldCode="AU" term="%22Machado+M%22">Machado M</searchLink>; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Gonçalves+L%22">Gonçalves L</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Sharma+M%22">Sharma M</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Gut+J%22">Gut J</searchLink>; Department of Medicine, San Francisco General Hospital, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA, 94110, USA.<br /><searchLink fieldCode="AU" term="%22Lukens+AK%22">Lukens AK</searchLink>; The Broad Institute, Infectious Diseases Program, Cambridge, MA, 02142, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Wirth+DF%22">Wirth DF</searchLink>; The Broad Institute, Infectious Diseases Program, Cambridge, MA, 02142, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22André+V%22">André V</searchLink>; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, 1049-001, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Duarte+MT%22">Duarte MT</searchLink>; Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, 1049-001, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Guedes+RC%22">Guedes RC</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+DJ%22">Dos Santos DJ</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.; LAQV@REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Rosenthal+PJ%22">Rosenthal PJ</searchLink>; Department of Medicine, San Francisco General Hospital, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA, 94110, USA.<br /><searchLink fieldCode="AU" term="%22Mazitschek+R%22">Mazitschek R</searchLink>; The Broad Institute, Infectious Diseases Program, Cambridge, MA, 02142, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Center for System Biology, Massachusetts General Hospital and Harvard Medical School, Richard B. Simches Research Center, 185 Cambridge Street, Boston, MA, 02114, USA.<br /><searchLink fieldCode="AU" term="%22Prudêncio+M%22">Prudêncio M</searchLink>; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal. mprudencio@medicina.ulisboa.pt.<br /><searchLink fieldCode="AU" term="%22Moreira+R%22">Moreira R</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
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