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Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors.

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Title: Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors.
Authors: Sommer A; Bayer Pharma AG, Berlin, Germany. anette.sommer@bayer.com., Kopitz C; Bayer Pharma AG, Berlin, Germany., Schatz CA; Bayer Pharma AG, Berlin, Germany., Nising CF; Bayer Pharma AG, Wuppertal, Germany., Mahlert C; Bayer Pharma AG, Wuppertal, Germany., Lerchen HG; Bayer Pharma AG, Wuppertal, Germany., Stelte-Ludwig B; Bayer Pharma AG, Wuppertal, Germany., Hammer S; Bayer Pharma AG, Berlin, Germany., Greven S; Bayer Pharma AG, Wuppertal, Germany., Schuhmacher J; Bayer Pharma AG, Wuppertal, Germany., Braun M; Bayer Pharma AG, Berlin, Germany., Zierz R; Bayer Pharma AG, Berlin, Germany., Wittemer-Rump S; Bayer Pharma AG, Berlin, Germany., Harrenga A; Bayer Intellectual Property GmbH, Monheim, Germany., Dittmer F; Bayer Pharma AG, Wuppertal, Germany., Reetz F; Bayer Pharma AG, Berlin, Germany., Apeler H; Bayer Pharma AG, Wuppertal, Germany., Jautelat R; Bayer Pharma AG, Wuppertal, Germany., Huynh H; National Cancer Center Singapore, Division of Cellular & Molecular Research, Singapore., Ziegelbauer K; Bayer Pharma AG, Berlin, Germany., Kreft B; Bayer Pharma AG, Berlin, Germany.
Source: Cancer research [Cancer Res] 2016 Nov 01; Vol. 76 (21), pp. 6331-6339. Date of Electronic Publication: 2016 Aug 19.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors.
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  Data: <searchLink fieldCode="AU" term="%22Sommer+A%22">Sommer A</searchLink>; Bayer Pharma AG, Berlin, Germany. anette.sommer@bayer.com.<br /><searchLink fieldCode="AU" term="%22Kopitz+C%22">Kopitz C</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schatz+CA%22">Schatz CA</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Nising+CF%22">Nising CF</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Mahlert+C%22">Mahlert C</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Lerchen+HG%22">Lerchen HG</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Stelte-Ludwig+B%22">Stelte-Ludwig B</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Hammer+S%22">Hammer S</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Greven+S%22">Greven S</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Schuhmacher+J%22">Schuhmacher J</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Braun+M%22">Braun M</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Zierz+R%22">Zierz R</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wittemer-Rump+S%22">Wittemer-Rump S</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Harrenga+A%22">Harrenga A</searchLink>; Bayer Intellectual Property GmbH, Monheim, Germany.<br /><searchLink fieldCode="AU" term="%22Dittmer+F%22">Dittmer F</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Reetz+F%22">Reetz F</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Apeler+H%22">Apeler H</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Jautelat+R%22">Jautelat R</searchLink>; Bayer Pharma AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Huynh+H%22">Huynh H</searchLink>; National Cancer Center Singapore, Division of Cellular & Molecular Research, Singapore.<br /><searchLink fieldCode="AU" term="%22Ziegelbauer+K%22">Ziegelbauer K</searchLink>; Bayer Pharma AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kreft+B%22">Kreft B</searchLink>; Bayer Pharma AG, Berlin, Germany.
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  Data: <searchLink fieldCode="JN" term="%222984705R%22">Cancer research</searchLink> [Cancer Res] 2016 Nov 01; Vol. 76 (21), pp. 6331-6339. <i>Date of Electronic Publication: </i>2016 Aug 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2984705R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7445 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200085472%22">00085472 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res <i>Subsets: </i>MEDLINE
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        Value: 10.1158/0008-5472.CAN-16-0180
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