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Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.

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Title: Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.
Authors: Zanotto-Filho A; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Departamento de Farmacologia, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.; Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Masamsetti VP; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Children's Medical Research Institute, Westmead, New South Wales, Australia., Loranc E; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas., Tonapi SS; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas., Gorthi A; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas., Bernard X; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas., Gonçalves RM; Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Moreira JC; Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Chen Y; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, Texas., Bishop AJ; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas. bishopa@uthscsa.edu.; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2016 Dec; Vol. 15 (12), pp. 3000-3014. Date of Electronic Publication: 2016 Sep 16.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.
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  Data: <searchLink fieldCode="AU" term="%22Zanotto-Filho+A%22">Zanotto-Filho A</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Departamento de Farmacologia, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.; Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Masamsetti+VP%22">Masamsetti VP</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Children's Medical Research Institute, Westmead, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Loranc+E%22">Loranc E</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Tonapi+SS%22">Tonapi SS</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Gorthi+A%22">Gorthi A</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Bernard+X%22">Bernard X</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Gonçalves+RM%22">Gonçalves RM</searchLink>; Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Moreira+JC%22">Moreira JC</searchLink>; Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Bishop+AJ%22">Bishop AJ</searchLink>; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas. bishopa@uthscsa.edu.; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
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  Data: <searchLink fieldCode="JN" term="%22101132535%22">Molecular cancer therapeutics</searchLink> [Mol Cancer Ther] 2016 Dec; Vol. 15 (12), pp. 3000-3014. <i>Date of Electronic Publication: </i>2016 Sep 16.
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              Text: 2016 Dec
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