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CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.

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Title: CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.
Authors: Dockree T; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Holland CJ; Faculty of Health Sciences, University of Bristol, Bristol, UK., Clement M; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Ladell K; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., McLaren JE; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., van den Berg HA; Mathematics Institute, University of Warwick, Coventry, UK., Gostick E; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., L Miners K; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Llewellyn-Lacey S; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Bridgeman JS; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK., Man S; Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, UK., Bailey M; Faculty of Health Sciences, University of Bristol, Bristol, UK., Burrows SR; Cellular Immunology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Price DA; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Wooldridge L; Faculty of Health Sciences, University of Bristol, Bristol, UK.
Source: Immunology and cell biology [Immunol Cell Biol] 2017 Jan; Vol. 95 (1), pp. 68-76. Date of Electronic Publication: 2016 Nov 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8706300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1711 (Electronic) Linking ISSN: 08189641 NLM ISO Abbreviation: Immunol Cell Biol Subsets: MEDLINE
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  Data: CD8<superscript>+</superscript> T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.
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