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High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.

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Title: High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.
Authors: Kannanganat S; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Wyatt LS; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892., Gangadhara S; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Chamcha V; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Chea LS; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Kozlowski PA; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112., LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC 27705; and., Chennareddi L; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Lawson B; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Reddy PB; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Styles TM; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Vanderford TH; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322., Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC 27705; and., Moss B; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892., Robinson HL; GeoVax, Inc., Smyrna, GA 30080 hrobinson@geovax.com ramara@emory.edu., Amara RR; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329; hrobinson@geovax.com ramara@emory.edu.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2016 Nov 01; Vol. 197 (9), pp. 3586-3596. Date of Electronic Publication: 2016 Sep 28.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
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  Data: High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.
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  Data: <searchLink fieldCode="AU" term="%22Kannanganat+S%22">Kannanganat S</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Wyatt+LS%22">Wyatt LS</searchLink>; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Gangadhara+S%22">Gangadhara S</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Chamcha+V%22">Chamcha V</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Chea+LS%22">Chea LS</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Kozlowski+PA%22">Kozlowski PA</searchLink>; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112.<br /><searchLink fieldCode="AU" term="%22LaBranche+CC%22">LaBranche CC</searchLink>; Department of Surgery, Duke University Medical Center, Durham, NC 27705; and.<br /><searchLink fieldCode="AU" term="%22Chennareddi+L%22">Chennareddi L</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Lawson+B%22">Lawson B</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Reddy+PB%22">Reddy PB</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Styles+TM%22">Styles TM</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Vanderford+TH%22">Vanderford TH</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Department of Surgery, Duke University Medical Center, Durham, NC 27705; and.<br /><searchLink fieldCode="AU" term="%22Moss+B%22">Moss B</searchLink>; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Robinson+HL%22">Robinson HL</searchLink>; GeoVax, Inc., Smyrna, GA 30080 hrobinson@geovax.com ramara@emory.edu.<br /><searchLink fieldCode="AU" term="%22Amara+RR%22">Amara RR</searchLink>; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329; hrobinson@geovax.com ramara@emory.edu.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322.
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