IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation.

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Title: IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation.
Authors: Sim GC; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. laszlo.radvanyi@emdserono.com gcsim1@yahoo.co.uk.; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Liu C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang E; Division of Translational Medicine, Sidra Medical and Research Center, Doha, Qatar., Liu H; Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland., Creasy C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Dai Z; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Overwijk WW; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Roszik J; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Marincola F; Division of Translational Medicine, Sidra Medical and Research Center, Doha, Qatar., Hwu P; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Grimm E; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Radvanyi L; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. laszlo.radvanyi@emdserono.com gcsim1@yahoo.co.uk.; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Source: Cancer immunology research [Cancer Immunol Res] 2016 Nov; Vol. 4 (11), pp. 983-994. Date of Electronic Publication: 2016 Oct 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation.
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  Data: <searchLink fieldCode="AU" term="%22Sim+GC%22">Sim GC</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. laszlo.radvanyi@emdserono.com gcsim1@yahoo.co.uk.; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Wang+E%22">Wang E</searchLink>; Division of Translational Medicine, Sidra Medical and Research Center, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Creasy+C%22">Creasy C</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Dai+Z%22">Dai Z</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Overwijk+WW%22">Overwijk WW</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Roszik+J%22">Roszik J</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Marincola+F%22">Marincola F</searchLink>; Division of Translational Medicine, Sidra Medical and Research Center, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Hwu+P%22">Hwu P</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Grimm+E%22">Grimm E</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Radvanyi+L%22">Radvanyi L</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. laszlo.radvanyi@emdserono.com gcsim1@yahoo.co.uk.; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
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  Data: <searchLink fieldCode="JN" term="%22101614637%22">Cancer immunology research</searchLink> [Cancer Immunol Res] 2016 Nov; Vol. 4 (11), pp. 983-994. <i>Date of Electronic Publication: </i>2016 Oct 03.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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