Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.
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| Title: | Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models. |
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| Authors: | Siner JI; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Samelson-Jones BJ; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Crudele JM; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., French RA; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Lee BJ; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Zhou S; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Merricks E; University of North Carolina, Chapel Hill, North Carolina, USA., Raymer R; University of North Carolina, Chapel Hill, North Carolina, USA., Nichols TC; University of North Carolina, Chapel Hill, North Carolina, USA., Camire RM; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Arruda VR; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. |
| Source: | JCI insight [JCI Insight] 2016 Oct 06; Vol. 1 (16), pp. e89371. Date of Electronic Publication: 2016 Oct 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Print ISSN: 2379-3708 (Print) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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