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Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition.

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Title: Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition.
Authors: Frost J; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Galdeano C; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Soares P; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Gadd MS; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Grzes KM; Division of Cell Signaling and Immunology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Ellis L; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Epemolu O; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Shimamura S; Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany., Bantscheff M; Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany., Grandi P; Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany., Read KD; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Cantrell DA; Division of Cell Signaling and Immunology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Rocha S; Center for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK., Ciulli A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.
Source: Nature communications [Nat Commun] 2016 Nov 04; Vol. 7, pp. 13312. Date of Electronic Publication: 2016 Nov 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Frost+J%22">Frost J</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Galdeano+C%22">Galdeano C</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Soares+P%22">Soares P</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Gadd+MS%22">Gadd MS</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Grzes+KM%22">Grzes KM</searchLink>; Division of Cell Signaling and Immunology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Ellis+L%22">Ellis L</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Epemolu+O%22">Epemolu O</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Shimamura+S%22">Shimamura S</searchLink>; Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Bantscheff+M%22">Bantscheff M</searchLink>; Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Grandi+P%22">Grandi P</searchLink>; Cellzome GmbH, Meyerhofstrasse 1, 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Read+KD%22">Read KD</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Cantrell+DA%22">Cantrell DA</searchLink>; Division of Cell Signaling and Immunology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Rocha+S%22">Rocha S</searchLink>; Center for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Ciulli+A%22">Ciulli A</searchLink>; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.
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