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Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms.

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Title: Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms.
Authors: Pieri L; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Paoli C; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Arena U; Internal Medicine and Hepatology, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy., Marra F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Mori F; Department of Cardiology, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy., Zucchini M; Department of Cardiology, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy., Colagrande S; Department of Experimental and Clinical Biomedical Sciences, University of Florence - Azienda Ospedaliera-Universitaria Careggi, Florence, Italy., Castellani A; Department of Experimental and Clinical Biomedical Sciences, University of Florence - Azienda Ospedaliera-Universitaria Careggi, Florence, Italy., Masciulli A; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy., Rosti V; IRCCS Policlinico San Matteo Foundation, Center for the Study of Myelofibrosis, Biotechnology Research Area, Pavia, Italy., De Stefano V; Institute of Hematology, Catholic University, Rome, Italy., Betti S; Institute of Hematology, Catholic University, Rome, Italy., Finazzi G; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy., Ferrari ML; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy., Rumi E; Department of Hematology Oncology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy., Ruggeri M; Department of Hematology, San Bortolo Hospital, Vicenza, Italy., Nichele I; Department of Hematology, San Bortolo Hospital, Vicenza, Italy., Guglielmelli P; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Fjerza R; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Mannarelli C; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Fanelli T; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; University of Siena, Siena, Italy., Merli L; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Corbizi Fattori G; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; University of Siena, Siena, Italy., Massa M; IRCCS Policlinico San Matteo Foundation, Biotechnology Research Area, Pavia, Italy., Cimino G; Department of Cellular Biotechnology and Hematology, University 'La Sapienza', Rome, Italy., Rambaldi A; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy., Barosi G; IRCCS Policlinico San Matteo Foundation, Center for the Study of Myelofibrosis, Biotechnology Research Area, Pavia, Italy., Cazzola M; Department of Hematology Oncology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy., Barbui T; Hospital Papa Giovanni XXIII and Research Foundation, Bergamo, Italy., Vannucchi AM; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Source: American journal of hematology [Am J Hematol] 2017 Feb; Vol. 92 (2), pp. 187-195.
Publication Type: Clinical Trial, Phase II; Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE
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  Data: Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms.
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  Data: <searchLink fieldCode="AU" term="%22Pieri+L%22">Pieri L</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Paoli+C%22">Paoli C</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Arena+U%22">Arena U</searchLink>; Internal Medicine and Hepatology, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Marra+F%22">Marra F</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Mori+F%22">Mori F</searchLink>; Department of Cardiology, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Zucchini+M%22">Zucchini M</searchLink>; Department of Cardiology, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Colagrande+S%22">Colagrande S</searchLink>; Department of Experimental and Clinical Biomedical Sciences, University of Florence - Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Castellani+A%22">Castellani A</searchLink>; Department of Experimental and Clinical Biomedical Sciences, University of Florence - Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Masciulli+A%22">Masciulli A</searchLink>; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Rosti+V%22">Rosti V</searchLink>; IRCCS Policlinico San Matteo Foundation, Center for the Study of Myelofibrosis, Biotechnology Research Area, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22De+Stefano+V%22">De Stefano V</searchLink>; Institute of Hematology, Catholic University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Betti+S%22">Betti S</searchLink>; Institute of Hematology, Catholic University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Finazzi+G%22">Finazzi G</searchLink>; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrari+ML%22">Ferrari ML</searchLink>; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Rumi+E%22">Rumi E</searchLink>; Department of Hematology Oncology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Ruggeri+M%22">Ruggeri M</searchLink>; Department of Hematology, San Bortolo Hospital, Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Nichele+I%22">Nichele I</searchLink>; Department of Hematology, San Bortolo Hospital, Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Guglielmelli+P%22">Guglielmelli P</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Fjerza+R%22">Fjerza R</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Mannarelli+C%22">Mannarelli C</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Fanelli+T%22">Fanelli T</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Merli+L%22">Merli L</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Corbizi+Fattori+G%22">Corbizi Fattori G</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Massa+M%22">Massa M</searchLink>; IRCCS Policlinico San Matteo Foundation, Biotechnology Research Area, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Cimino+G%22">Cimino G</searchLink>; Department of Cellular Biotechnology and Hematology, University 'La Sapienza', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rambaldi+A%22">Rambaldi A</searchLink>; Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Barosi+G%22">Barosi G</searchLink>; IRCCS Policlinico San Matteo Foundation, Center for the Study of Myelofibrosis, Biotechnology Research Area, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Cazzola+M%22">Cazzola M</searchLink>; Department of Hematology Oncology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Barbui+T%22">Barbui T</searchLink>; Hospital Papa Giovanni XXIII and Research Foundation, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Vannucchi+AM%22">Vannucchi AM</searchLink>; CRIMM-Centro Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.; DenoThe Excellence Center, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
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