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Variable ventilation improves pulmonary function and reduces lung damage without increasing bacterial translocation in a rat model of experimental pneumonia.

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Title: Variable ventilation improves pulmonary function and reduces lung damage without increasing bacterial translocation in a rat model of experimental pneumonia.
Authors: de Magalhães RF; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Samary CS; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Santos RS; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., de Oliveira MV; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Rocha NN; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Santos CL; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Kitoko J; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Silva CA; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil., Hildebrandt CL; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil., Goncalves-de-Albuquerque CF; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil., Silva AR; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil., Faria-Neto HC; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil., Martins V; Department of Pathology, University of São Paulo, Av. Doutor Arnaldo, 455, 01246-903, São Paulo, SP, Brazil., Capelozzi VL; Department of Pathology, University of São Paulo, Av. Doutor Arnaldo, 455, 01246-903, São Paulo, SP, Brazil., Huhle R; Pulmonary Engineering Group, Department of Anesthesiology and Intensive Care Therapy, University Hospital Carl Gustav Carus, Dresden University of Technology, Fetschertsrasse 74, 01307, Dresden, Germany., Morales MM; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Biophysics Institute, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G2-048, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Olsen P; Laboratory of Clinical Bacteriology and Immunology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Carlos Chagas Filho Biophysics Institute, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G2-048, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Pelosi P; IRCCS AOU San Martino-IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Largo Rosanna Benzi 8, 16132, Genoa, Italy., de Abreu MG; Pulmonary Engineering Group, Department of Anesthesiology and Intensive Care Therapy, University Hospital Carl Gustav Carus, Dresden University of Technology, Fetschertsrasse 74, 01307, Dresden, Germany., Rocco PR; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Silva PL; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil. pedro.leme@gmail.com.; Laboratory of Pulmonary Investigation, Centro de Ciências da Saúde, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil. pedro.leme@gmail.com.
Source: Respiratory research [Respir Res] 2016 Nov 25; Vol. 17 (1), pp. 158. Date of Electronic Publication: 2016 Nov 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Variable ventilation improves pulmonary function and reduces lung damage without increasing bacterial translocation in a rat model of experimental pneumonia.
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  Data: <searchLink fieldCode="AU" term="%22de+Magalhães+RF%22">de Magalhães RF</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Samary+CS%22">Samary CS</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Santos+RS%22">Santos RS</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+MV%22">de Oliveira MV</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocha+NN%22">Rocha NN</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Santos+CL%22">Santos CL</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Kitoko+J%22">Kitoko J</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+CA%22">Silva CA</searchLink>; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Hildebrandt+CL%22">Hildebrandt CL</searchLink>; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Goncalves-de-Albuquerque+CF%22">Goncalves-de-Albuquerque CF</searchLink>; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+AR%22">Silva AR</searchLink>; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Faria-Neto+HC%22">Faria-Neto HC</searchLink>; Laboratory of Immunopharmacology, Oswaldo Cruz Institute - Fiocruz, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Martins+V%22">Martins V</searchLink>; Department of Pathology, University of São Paulo, Av. Doutor Arnaldo, 455, 01246-903, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Capelozzi+VL%22">Capelozzi VL</searchLink>; Department of Pathology, University of São Paulo, Av. Doutor Arnaldo, 455, 01246-903, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Huhle+R%22">Huhle R</searchLink>; Pulmonary Engineering Group, Department of Anesthesiology and Intensive Care Therapy, University Hospital Carl Gustav Carus, Dresden University of Technology, Fetschertsrasse 74, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Morales+MM%22">Morales MM</searchLink>; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Biophysics Institute, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G2-048, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Olsen+P%22">Olsen P</searchLink>; Laboratory of Clinical Bacteriology and Immunology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Carlos Chagas Filho Biophysics Institute, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G2-048, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Pelosi+P%22">Pelosi P</searchLink>; IRCCS AOU San Martino-IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Largo Rosanna Benzi 8, 16132, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22de+Abreu+MG%22">de Abreu MG</searchLink>; Pulmonary Engineering Group, Department of Anesthesiology and Intensive Care Therapy, University Hospital Carl Gustav Carus, Dresden University of Technology, Fetschertsrasse 74, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Rocco+PR%22">Rocco PR</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+PL%22">Silva PL</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil. pedro.leme@gmail.com.; Laboratory of Pulmonary Investigation, Centro de Ciências da Saúde, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil. pedro.leme@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101090633%22">Respiratory research</searchLink> [Respir Res] 2016 Nov 25; Vol. 17 (1), pp. 158. <i>Date of Electronic Publication: </i>2016 Nov 25.
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