Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials.

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Title: Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials.
Authors: McKenna DH Jr; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA. Electronic address: mcken020@umn.edu., Sumstad D; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Kadidlo DM; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Batdorf B; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Lord CJ; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Merkel SC; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Koellner CM; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Curtsinger JM; Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., June CH; Department of Pathology and Laboratory Medicine, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA; Abramson Family Cancer Center Research Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA., Riley JL; Abramson Family Cancer Center Research Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA; Department of Microbiology, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA., Levine BL; Department of Pathology and Laboratory Medicine, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA; Abramson Family Cancer Center Research Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA., Miller JS; Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Brunstein CG; Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Wagner JE; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Blazar BR; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA., Hippen KL; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA. Electronic address: hippe002@umn.edu.
Source: Cytotherapy [Cytotherapy] 2017 Feb; Vol. 19 (2), pp. 250-262. Date of Electronic Publication: 2016 Nov 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 100895309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2566 (Electronic) Linking ISSN: 14653249 NLM ISO Abbreviation: Cytotherapy Subsets: MEDLINE
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  Data: Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials.
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  Data: <searchLink fieldCode="AU" term="%22McKenna+DH+Jr%22">McKenna DH Jr</searchLink>; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA. Electronic address: mcken020@umn.edu.<br /><searchLink fieldCode="AU" term="%22Sumstad+D%22">Sumstad D</searchLink>; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Kadidlo+DM%22">Kadidlo DM</searchLink>; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Batdorf+B%22">Batdorf B</searchLink>; Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Lord+CJ%22">Lord CJ</searchLink>; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Merkel+SC%22">Merkel SC</searchLink>; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Koellner+CM%22">Koellner CM</searchLink>; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Curtsinger+JM%22">Curtsinger JM</searchLink>; Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22June+CH%22">June CH</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA; Abramson Family Cancer Center Research Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Riley+JL%22">Riley JL</searchLink>; Abramson Family Cancer Center Research Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA; Department of Microbiology, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Levine+BL%22">Levine BL</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA; Abramson Family Cancer Center Research Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Miller+JS%22">Miller JS</searchLink>; Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Brunstein+CG%22">Brunstein CG</searchLink>; Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Wagner+JE%22">Wagner JE</searchLink>; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Blazar+BR%22">Blazar BR</searchLink>; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Hippen+KL%22">Hippen KL</searchLink>; Department of Pediatrics, Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis/Saint Paul, Minnesota, USA. Electronic address: hippe002@umn.edu.
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  Data: <searchLink fieldCode="JN" term="%22100895309%22">Cytotherapy</searchLink> [Cytotherapy] 2017 Feb; Vol. 19 (2), pp. 250-262. <i>Date of Electronic Publication: </i>2016 Nov 22.
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        Value: 10.1016/j.jcyt.2016.10.011
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              Text: 2017 Feb
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