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Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding.

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Title: Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding.
Authors: Ungelenk S; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany., Moayed F; FOM Institute for Atomic and Molecular Physics (AMOLF), Science Park 104, Amsterdam 1098 XG, The Netherlands., Ho CT; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany., Grousl T; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany., Scharf A; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany., Mashaghi A; FOM Institute for Atomic and Molecular Physics (AMOLF), Science Park 104, Amsterdam 1098 XG, The Netherlands., Tans S; FOM Institute for Atomic and Molecular Physics (AMOLF), Science Park 104, Amsterdam 1098 XG, The Netherlands., Mayer MP; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany., Mogk A; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany., Bukau B; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany.
Source: Nature communications [Nat Commun] 2016 Nov 30; Vol. 7, pp. 13673. Date of Electronic Publication: 2016 Nov 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ungelenk+S%22">Ungelenk S</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany.<br /><searchLink fieldCode="AU" term="%22Moayed+F%22">Moayed F</searchLink>; FOM Institute for Atomic and Molecular Physics (AMOLF), Science Park 104, Amsterdam 1098 XG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ho+CT%22">Ho CT</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany.<br /><searchLink fieldCode="AU" term="%22Grousl+T%22">Grousl T</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany.<br /><searchLink fieldCode="AU" term="%22Scharf+A%22">Scharf A</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.<br /><searchLink fieldCode="AU" term="%22Mashaghi+A%22">Mashaghi A</searchLink>; FOM Institute for Atomic and Molecular Physics (AMOLF), Science Park 104, Amsterdam 1098 XG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tans+S%22">Tans S</searchLink>; FOM Institute for Atomic and Molecular Physics (AMOLF), Science Park 104, Amsterdam 1098 XG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mayer+MP%22">Mayer MP</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.<br /><searchLink fieldCode="AU" term="%22Mogk+A%22">Mogk A</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany.<br /><searchLink fieldCode="AU" term="%22Bukau+B%22">Bukau B</searchLink>; Center for Molecular Biology of the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg D-69120, Germany.; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg D-69120, Germany.
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