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Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis.

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Title: Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis.
Authors: Thorek DL; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Radiological Science, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Watson PA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Lee SG; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Ku AT; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Bournazos S; Leonard Wagner Laboratory of Molecular Genetics and Immunology, Rockefeller University, New York, NY 10065, USA., Braun K; Department of Urology, University Hospital of the Ruhr-University of Bochum, Marien Hospital Herne, Herne, Germany., Kim K; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Sjöström K; Innovagen AB, Lund, Sweden., Doran MG; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Lamminmäki U; Department of Biochemistry, University of Turku, Turku, Finland., Santos E; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Veach D; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA., Turkekul M; Molecular Cytology Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Casey E; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Lewis JS; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Radiochemistry and Imaging Sciences Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Abou DS; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Radiological Science, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., van Voss MR; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Radiological Science, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, University Medical Center Utrecht, Utrecht, Netherlands., Scardino PT; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Urology, Weill Cornell Medical College, New York, NY 10065, USA., Strand SE; Department of Medical Radiation Physics, Lund University, Lund, Sweden., Alpaugh ML; Departments of Biology and Biomedical and Translational Sciences, Rowan University, Glassboro, NJ 08028, USA., Scher HI; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., Lilja H; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ulmerth@mskcc.org liljah@mskcc.org larsons@mskcc.org.; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, U.K.; Department of Laboratory Medicine, Lund University, Malmö, Sweden., Larson SM; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ulmerth@mskcc.org liljah@mskcc.org larsons@mskcc.org.; Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA., Ulmert D; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ulmerth@mskcc.org liljah@mskcc.org larsons@mskcc.org.; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Division of Urological Research, Department of Clinical Sciences, Lund University, Malmö, Sweden.
Source: Science translational medicine [Sci Transl Med] 2016 Nov 30; Vol. 8 (367), pp. 367ra167.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis.
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  Data: <searchLink fieldCode="AU" term="%22Thorek+DL%22">Thorek DL</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Radiological Science, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Watson+PA%22">Watson PA</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Lee+SG%22">Lee SG</searchLink>; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Ku+AT%22">Ku AT</searchLink>; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Bournazos+S%22">Bournazos S</searchLink>; Leonard Wagner Laboratory of Molecular Genetics and Immunology, Rockefeller University, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Braun+K%22">Braun K</searchLink>; Department of Urology, University Hospital of the Ruhr-University of Bochum, Marien Hospital Herne, Herne, Germany.<br /><searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Sjöström+K%22">Sjöström K</searchLink>; Innovagen AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Doran+MG%22">Doran MG</searchLink>; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Lamminmäki+U%22">Lamminmäki U</searchLink>; Department of Biochemistry, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Santos+E%22">Santos E</searchLink>; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Veach+D%22">Veach D</searchLink>; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Turkekul+M%22">Turkekul M</searchLink>; Molecular Cytology Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Casey+E%22">Casey E</searchLink>; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+JS%22">Lewis JS</searchLink>; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Radiochemistry and Imaging Sciences Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Abou+DS%22">Abou DS</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Radiological Science, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22van+Voss+MR%22">van Voss MR</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Radiological Science, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, University Medical Center Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Scardino+PT%22">Scardino PT</searchLink>; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Urology, Weill Cornell Medical College, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Strand+SE%22">Strand SE</searchLink>; Department of Medical Radiation Physics, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Alpaugh+ML%22">Alpaugh ML</searchLink>; Departments of Biology and Biomedical and Translational Sciences, Rowan University, Glassboro, NJ 08028, USA.<br /><searchLink fieldCode="AU" term="%22Scher+HI%22">Scher HI</searchLink>; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Lilja+H%22">Lilja H</searchLink>; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ulmerth@mskcc.org liljah@mskcc.org larsons@mskcc.org.; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, U.K.; Department of Laboratory Medicine, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Larson+SM%22">Larson SM</searchLink>; Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ulmerth@mskcc.org liljah@mskcc.org larsons@mskcc.org.; Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Ulmert+D%22">Ulmert D</searchLink>; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ulmerth@mskcc.org liljah@mskcc.org larsons@mskcc.org.; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Division of Urological Research, Department of Clinical Sciences, Lund University, Malmö, Sweden.
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