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Disease variants alter transcription factor levels and methylation of their binding sites.

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Title: Disease variants alter transcription factor levels and methylation of their binding sites.
Authors: Bonder MJ; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Luijk R; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Zhernakova DV; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Moed M; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Deelen P; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands., Vermaat M; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., van Iterson M; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., van Dijk F; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands., van Galen M; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands., Bot J; SURFsara, Amsterdam, the Netherlands., Slieker RC; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Jhamai PM; Department of Internal Medicine, ErasmusMC, Rotterdam, the Netherlands., Verbiest M; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands., Suchiman HE; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Verkerk M; Department of Internal Medicine, ErasmusMC, Rotterdam, the Netherlands., van der Breggen R; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., van Rooij J; Department of Internal Medicine, ErasmusMC, Rotterdam, the Netherlands., Lakenberg N; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Arindrarto W; Medical Statistics Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Kielbasa SM; Sequence Analysis Support Core, Leiden University Medical Center, Leiden, the Netherlands., Jonkers I; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., van 't Hof P; Sequence Analysis Support Core, Leiden University Medical Center, Leiden, the Netherlands., Nooren I; SURFsara, Amsterdam, the Netherlands., Beekman M; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Deelen J; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Zhernakova A; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Tigchelaar EF; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Swertz MA; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands., Hofman A; Department of Epidemiology, ErasmusMC, Rotterdam, the Netherlands., Uitterlinden AG; Department of Internal Medicine, ErasmusMC, Rotterdam, the Netherlands., Pool R; Department of Biological Psychology, Vrije Universiteit Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., van Dongen J; Department of Biological Psychology, Vrije Universiteit Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., Stehouwer CD; Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., van der Kallen CJ; Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., Schalkwijk CG; Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., van den Berg LH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., van Zwet EW; Medical Statistics Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Mei H; Sequence Analysis Support Core, Leiden University Medical Center, Leiden, the Netherlands., Li Y; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Lemire M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Hudson TJ; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Slagboom PE; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Wijmenga C; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Veldink JH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., van Greevenbroek MM; Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, ErasmusMC, Rotterdam, the Netherlands., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., Isaacs A; School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands.; Genetic Epidemiology Unit, Department of Epidemiology, ErasmusMC, Rotterdam, the Netherlands.; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, the Netherlands., Jansen R; Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., van Meurs JB; Department of Internal Medicine, ErasmusMC, Rotterdam, the Netherlands., 't Hoen PA; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Franke L; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands., Heijmans BT; Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands.
Corporate Authors: BIOS Consortium
Source: Nature genetics [Nat Genet] 2017 Jan; Vol. 49 (1), pp. 131-138. Date of Electronic Publication: 2016 Dec 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disease variants alter transcription factor levels and methylation of their binding sites.
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            NameFull: Isaacs A
      – PersonEntity:
          Name:
            NameFull: Jansen R
      – PersonEntity:
          Name:
            NameFull: van Meurs JB
      – PersonEntity:
          Name:
            NameFull: 't Hoen PA
      – PersonEntity:
          Name:
            NameFull: Franke L
      – PersonEntity:
          Name:
            NameFull: Heijmans BT
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: 2017 Jan
              Type: published
              Y: 2017
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 49
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1