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Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques.

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Title: Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques.
Authors: Kasturi SP; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Kozlowski PA; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA., Nakaya HI; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil., Burger MC; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil., Russo P; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil., Pham M; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Kovalenkov Y; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Silveira ELV; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil., Havenar-Daughton C; Division of Vaccine Discovery, La Jolla Institute of Allergy and Immunology, La Jolla, California, USA., Burton SL; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Kilgore KM; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Johnson MJ; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Nabi R; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA., Legere T; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Sher ZJ; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Chen X; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Amara RR; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Division of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, USA., Hunter E; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pathology and Laboratory Medicine, Atlanta, Georgia, USA., Bosinger SE; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA., Spearman P; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Crotty S; Division of Vaccine Discovery, La Jolla Institute of Allergy and Immunology, La Jolla, California, USA., Villinger F; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; New Iberia Research Center, University of Louisiana Lafayette, New Iberia, Louisiana, USA., Derdeyn CA; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pathology and Laboratory Medicine, Atlanta, Georgia, USA., Wrammert J; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Pulendran B; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA bpulend@emory.edu.; Department of Pathology and Laboratory Medicine, Atlanta, Georgia, USA.
Source: Journal of virology [J Virol] 2017 Jan 31; Vol. 91 (4). Date of Electronic Publication: 2017 Jan 31 (Print Publication: 2017).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE
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  Data: Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques.
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  Data: <searchLink fieldCode="AU" term="%22Kasturi+SP%22">Kasturi SP</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Kozlowski+PA%22">Kozlowski PA</searchLink>; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Nakaya+HI%22">Nakaya HI</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Burger+MC%22">Burger MC</searchLink>; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Russo+P%22">Russo P</searchLink>; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Pham+M%22">Pham M</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Kovalenkov+Y%22">Kovalenkov Y</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Silveira+ELV%22">Silveira ELV</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Faculty of Pharmaceutical Sciences, Department of Clinical and Toxicological Analyses, University of Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Havenar-Daughton+C%22">Havenar-Daughton C</searchLink>; Division of Vaccine Discovery, La Jolla Institute of Allergy and Immunology, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Burton+SL%22">Burton SL</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Kilgore+KM%22">Kilgore KM</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+MJ%22">Johnson MJ</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Nabi+R%22">Nabi R</searchLink>; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Legere+T%22">Legere T</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Sher+ZJ%22">Sher ZJ</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Amara+RR%22">Amara RR</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Division of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Hunter+E%22">Hunter E</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pathology and Laboratory Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Bosinger+SE%22">Bosinger SE</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Spearman+P%22">Spearman P</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Crotty+S%22">Crotty S</searchLink>; Division of Vaccine Discovery, La Jolla Institute of Allergy and Immunology, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Villinger+F%22">Villinger F</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; New Iberia Research Center, University of Louisiana Lafayette, New Iberia, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Derdeyn+CA%22">Derdeyn CA</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pathology and Laboratory Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Wrammert+J%22">Wrammert J</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Pulendran+B%22">Pulendran B</searchLink>; Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, USA bpulend@emory.edu.; Department of Pathology and Laboratory Medicine, Atlanta, Georgia, USA.
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  Data: <searchLink fieldCode="JN" term="%220113724%22">Journal of virology</searchLink> [J Virol] 2017 Jan 31; Vol. 91 (4). <i>Date of Electronic Publication: </i>2017 Jan 31 (<i>Print Publication: </i>2017).
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