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The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

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Title: The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
Authors: van Kempen LC; Department of Pathology, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada., Redpath M; Department of Pathology, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada., Elchebly M; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada., Klein KO; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada., Papadakis AI; Department of Pathology, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada., Wilmott JS; Melanoma Institute Australia, Royal Prince Alfred Hospital, and University of Sydney, Sydney, New South Wales, Australia., Scolyer RA; Melanoma Institute Australia, Royal Prince Alfred Hospital, and University of Sydney, Sydney, New South Wales, Australia., Edqvist PH; Department of Immunology, Genetics and Pathology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Pontén F; Department of Immunology, Genetics and Pathology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Schadendorf D; Department of Dermatology, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., van Rijk AF; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada., Michiels S; Service de Biostatistique et d'Epidémiologie, Gustave Roussy, Villejuif, France.; Centre for Research in Epidemiology and Population Health (CESP), INSERM, UMR 1018, Université Paris-Sud, Kremlin-Bicetre, France., Dumay A; Centre de Recherche sur l'Inflammation, INSERM, UMR S 1149, Labex Inflamex, Université Paris-Diderot Sorbonne Paris-Cité, Paris, France., Helbling-Leclerc A; CNRS, UMR 8200, Université Paris-Sud, Villejuif, France.; CNRS UMR 8200, Universite Paris-Sud, Gustave Roussy, Villejuif, France., Dessen P; Hématopoïèse normale et pathologique, INSERM UMR 1170, Université Paris-Sud, Gustave Roussy, Villejuif, France., Wouters J; Laboratory of Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.; Laboratory of Computational Biology, VIB Center for the Biology of Disease, KU Leuven, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Stass M; Department of Surgical Oncology, University Hospitals Leuven, KU Leuven, Leuven, Belgium., Greenwood CM; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada.; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada., Ghanem GE; Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium., van den Oord J; Laboratory of Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium., Feunteun J; CNRS UMR 8200, Universite Paris-Sud, Gustave Roussy, Villejuif, France., Spatz A; Department of Pathology, McGill University, Montreal, Quebec, Canada. alan.spatz@mcgill.ca.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada.
Source: Science translational medicine [Sci Transl Med] 2016 Dec 14; Vol. 8 (369), pp. 369ra177.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
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  Data: <searchLink fieldCode="AU" term="%22van+Kempen+LC%22">van Kempen LC</searchLink>; Department of Pathology, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Redpath+M%22">Redpath M</searchLink>; Department of Pathology, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Elchebly+M%22">Elchebly M</searchLink>; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Klein+KO%22">Klein KO</searchLink>; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Papadakis+AI%22">Papadakis AI</searchLink>; Department of Pathology, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Wilmott+JS%22">Wilmott JS</searchLink>; Melanoma Institute Australia, Royal Prince Alfred Hospital, and University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Scolyer+RA%22">Scolyer RA</searchLink>; Melanoma Institute Australia, Royal Prince Alfred Hospital, and University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Edqvist+PH%22">Edqvist PH</searchLink>; Department of Immunology, Genetics and Pathology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Pontén+F%22">Pontén F</searchLink>; Department of Immunology, Genetics and Pathology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Schadendorf+D%22">Schadendorf D</searchLink>; Department of Dermatology, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22van+Rijk+AF%22">van Rijk AF</searchLink>; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Michiels+S%22">Michiels S</searchLink>; Service de Biostatistique et d'Epidémiologie, Gustave Roussy, Villejuif, France.; Centre for Research in Epidemiology and Population Health (CESP), INSERM, UMR 1018, Université Paris-Sud, Kremlin-Bicetre, France.<br /><searchLink fieldCode="AU" term="%22Dumay+A%22">Dumay A</searchLink>; Centre de Recherche sur l'Inflammation, INSERM, UMR S 1149, Labex Inflamex, Université Paris-Diderot Sorbonne Paris-Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Helbling-Leclerc+A%22">Helbling-Leclerc A</searchLink>; CNRS, UMR 8200, Université Paris-Sud, Villejuif, France.; CNRS UMR 8200, Universite Paris-Sud, Gustave Roussy, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Dessen+P%22">Dessen P</searchLink>; Hématopoïèse normale et pathologique, INSERM UMR 1170, Université Paris-Sud, Gustave Roussy, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Wouters+J%22">Wouters J</searchLink>; Laboratory of Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.; Laboratory of Computational Biology, VIB Center for the Biology of Disease, KU Leuven, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Stass+M%22">Stass M</searchLink>; Department of Surgical Oncology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Greenwood+CM%22">Greenwood CM</searchLink>; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada.; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Ghanem+GE%22">Ghanem GE</searchLink>; Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22van+den+Oord+J%22">van den Oord J</searchLink>; Laboratory of Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Feunteun+J%22">Feunteun J</searchLink>; CNRS UMR 8200, Universite Paris-Sud, Gustave Roussy, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Spatz+A%22">Spatz A</searchLink>; Department of Pathology, McGill University, Montreal, Quebec, Canada. alan.spatz@mcgill.ca.; Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada.
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