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Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

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Title: Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.
Authors: Salla M; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Butler MS; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Pelingon R; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Kaeslin G; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Croker DE; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Reid JC; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Baek JM; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia., Bernhardt PV; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia., Gillam EM; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia., Cooper MA; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia., Robertson AA; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2016 Sep 27; Vol. 7 (12), pp. 1034-1038. Date of Electronic Publication: 2016 Sep 27 (Print Publication: 2016).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.
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  Data: <searchLink fieldCode="AU" term="%22Salla+M%22">Salla M</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Butler+MS%22">Butler MS</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Pelingon+R%22">Pelingon R</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Kaeslin+G%22">Kaeslin G</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Croker+DE%22">Croker DE</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Reid+JC%22">Reid JC</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Baek+JM%22">Baek JM</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Bernhardt+PV%22">Bernhardt PV</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Gillam+EM%22">Gillam EM</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Cooper+MA%22">Cooper MA</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Robertson+AA%22">Robertson AA</searchLink>; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101521073%22">ACS medicinal chemistry letters</searchLink> [ACS Med Chem Lett] 2016 Sep 27; Vol. 7 (12), pp. 1034-1038. <i>Date of Electronic Publication: </i>2016 Sep 27 (<i>Print Publication: </i>2016).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101521073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1948-5875 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219485875%22">19485875 </searchLink><i>NLM ISO Abbreviation: </i>ACS Med Chem Lett <i>Subsets: </i>PubMed not MEDLINE
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