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Paradoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis.

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Title: Paradoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis.
Authors: Müller CP; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany. Christian.Mueller@uk-erlangen.de., Kalinichenko LS; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Tiesel J; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Witt M; Bruker Daltonik GmbH, Bremen, Germany., Stöckl T; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Sprenger E; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Fuchser J; Bruker Daltonik GmbH, Bremen, Germany., Beckmann J; Bruker Daltonik GmbH, Bremen, Germany., Praetner M; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Huber SE; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Amato D; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Mühle C; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany., Büttner C; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Ekici AB; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Smaga I; Chair of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland., Pomierny-Chamiolo L; Chair of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland., Pomierny B; Chair of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland., Filip M; Institute of Pharmacology, Polish Academy of Sciences, Laboratory of Drug Addiction Pharmacology, 12 Smetna, Krakow, 31-343, Poland., Eulenburg V; Institute of Biochemistry, Friedrich-Alexander-University of Erlangen-Nuremberg, 91054, Erlangen, Germany., Gulbins E; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.; Department of Surgery, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH, 45267-0558, USA., Lourdusamy A; Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham, NG7 2UH, UK., Reichel M; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany.; Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nuremberg, Schwabachanlage 12, 91054, Erlangen, Germany., Kornhuber J; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany.
Source: Acta neuropathologica [Acta Neuropathol] 2017 Mar; Vol. 133 (3), pp. 463-483. Date of Electronic Publication: 2016 Dec 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
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  Data: Paradoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis.
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