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Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.

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Title: Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.
Authors: Pye CR; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Hewitt WM; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Schwochert J; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Haddad TD; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Townsend CE; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Etienne L; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Lao Y; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States., Limberakis C; World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. , Groton, Connecticut 06340, United States., Furukawa A; Modality Research Laboratories, Daiichi Sankyo Co., Ltd. , 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan., Mathiowetz AM; World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. , Cambridge, Massachusetts 02139, United States., Price DA; World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. , Cambridge, Massachusetts 02139, United States., Liras S; World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. , Cambridge, Massachusetts 02139, United States., Lokey RS; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2017 Mar 09; Vol. 60 (5), pp. 1665-1672. Date of Electronic Publication: 2017 Jan 25.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
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  Data: Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.
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  Data: <searchLink fieldCode="AU" term="%22Pye+CR%22">Pye CR</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Hewitt+WM%22">Hewitt WM</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Schwochert+J%22">Schwochert J</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Haddad+TD%22">Haddad TD</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Townsend+CE%22">Townsend CE</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Etienne+L%22">Etienne L</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Lao+Y%22">Lao Y</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.<br /><searchLink fieldCode="AU" term="%22Limberakis+C%22">Limberakis C</searchLink>; World Wide Medicinal Chemistry, Groton Laboratories, Pfizer Inc. , Groton, Connecticut 06340, United States.<br /><searchLink fieldCode="AU" term="%22Furukawa+A%22">Furukawa A</searchLink>; Modality Research Laboratories, Daiichi Sankyo Co., Ltd. , 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan.<br /><searchLink fieldCode="AU" term="%22Mathiowetz+AM%22">Mathiowetz AM</searchLink>; World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Price+DA%22">Price DA</searchLink>; World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Liras+S%22">Liras S</searchLink>; World Wide Medicinal Chemistry, Cambridge Laboratories, Pfizer Inc. , Cambridge, Massachusetts 02139, United States.<br /><searchLink fieldCode="AU" term="%22Lokey+RS%22">Lokey RS</searchLink>; Department of Chemistry and Biochemistry, University of California , Santa Cruz, California 95064, United States.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2017 Mar 09; Vol. 60 (5), pp. 1665-1672. <i>Date of Electronic Publication: </i>2017 Jan 25.
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