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Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.

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Title: Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.
Authors: Taylor RA; Monash Partners Comprehensive Cancer Consortium and Cancer Program, Biomedicine Discovery Institute, Department of Physiology, Monash University, Melbourne, Victoria 3800, Australia., Fraser M; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 1L7., Livingstone J; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Espiritu SM; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Thorne H; kConFab, Research Department, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; The Sir Peter MacCallum Department of Oncology University of Melbourne, Parkville, Victoria 3010, Australia., Huang V; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Lo W; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 1L7., Shiah YJ; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Yamaguchi TN; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Sliwinski A; The Sir Peter MacCallum Department of Oncology University of Melbourne, Parkville, Victoria 3010, Australia.; Department of Urology, University of Melbourne, Austin Hospital, Heidelberg, Victoria 3084, Australia., Horsburgh S; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 1L7., Meng A; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 1L7., Heisler LE; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Yu N; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Yousif F; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Papargiris M; Monash Partners Comprehensive Cancer Consortium and Cancer Program Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria 3800, Australia., Lawrence MG; Monash Partners Comprehensive Cancer Consortium and Cancer Program Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria 3800, Australia., Timms L; Genome Technologies Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Murphy DG; Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia., Frydenberg M; Monash Partners Comprehensive Cancer Consortium and Cancer Program Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria 3800, Australia., Hopkins JF; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., Bolton D; Monash Partners Comprehensive Cancer Consortium and Cancer Program Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria 3800, Australia., Clouston D; Urological Pathology, Tissupath, Mt Waverley, Victoria 3149, Australia., McPherson JD; Genome Technologies Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3., van der Kwast T; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 1L7., Boutros PC; Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada M5G 0A3.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 1L7.; Department of Pharmacology &Toxicology, University of Toronto, Toronto, Ontario, Canada M5S 1A8., Risbridger GP; Monash Partners Comprehensive Cancer Consortium and Cancer Program Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria 3800, Australia., Bristow RG; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 1L7.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 1L7.
Source: Nature communications [Nat Commun] 2017 Jan 09; Vol. 8, pp. 13671. Date of Electronic Publication: 2017 Jan 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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