Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function.

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Title: Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function.
Authors: Betts BC; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA. brian.betts@moffitt.org.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Veerapathran A; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA., Pidala J; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Yang H; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Horna P; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, FL 33612, USA., Walton K; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA., Cubitt CL; Translational Research Core, Moffitt Cancer Center, Tampa, FL 33612, USA., Gunawan S; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Lawrence HR; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Lawrence NJ; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Sebti SM; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Anasetti C; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.
Source: Science translational medicine [Sci Transl Med] 2017 Jan 11; Vol. 9 (372).
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function.
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  Data: <searchLink fieldCode="AU" term="%22Betts+BC%22">Betts BC</searchLink>; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA. brian.betts@moffitt.org.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Veerapathran+A%22">Veerapathran A</searchLink>; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Pidala+J%22">Pidala J</searchLink>; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Horna+P%22">Horna P</searchLink>; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Walton+K%22">Walton K</searchLink>; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Cubitt+CL%22">Cubitt CL</searchLink>; Translational Research Core, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Gunawan+S%22">Gunawan S</searchLink>; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Lawrence+HR%22">Lawrence HR</searchLink>; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Lawrence+NJ%22">Lawrence NJ</searchLink>; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Sebti+SM%22">Sebti SM</searchLink>; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22Anasetti+C%22">Anasetti C</searchLink>; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2017 Jan 11; Vol. 9 (372).
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        Value: 10.1126/scitranslmed.aai8269
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              Text: 2017 Jan 11
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