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Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies.

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Title: Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies.
Authors: de Vlaming R; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands., Okbay A; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands., Rietveld CA; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, Sweden., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Uitterlinden AG; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., van Rooij FJ; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Hofman A; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America., Groenen PJ; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Econometric Institute, Erasmus School of Economics, Rotterdam, the Netherlands., Thurik AR; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Montpellier Business School, Montpellier, France., Koellinger PD; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.
Source: PLoS genetics [PLoS Genet] 2017 Jan 17; Vol. 13 (1), pp. e1006495. Date of Electronic Publication: 2017 Jan 17 (Print Publication: 2017).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22de+Vlaming+R%22">de Vlaming R</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Okbay+A%22">Okbay A</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rietveld+CA%22">Rietveld CA</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Johannesson+M%22">Johannesson M</searchLink>; Department of Economics, Stockholm School of Economics, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Magnusson+PK%22">Magnusson PK</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Uitterlinden+AG%22">Uitterlinden AG</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Rooij+FJ%22">van Rooij FJ</searchLink>; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hofman+A%22">Hofman A</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Groenen+PJ%22">Groenen PJ</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Econometric Institute, Erasmus School of Economics, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Thurik+AR%22">Thurik AR</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Montpellier Business School, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Koellinger+PD%22">Koellinger PD</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.
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