First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288.
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| Title: | First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. |
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| Authors: | Gee KW; 1 Department of Pharmacology, School of Medicine, University of California Irvine, Irvine, USA., Olincy A; 2 Department of Psychiatry, University of Colorado School of Medicine, Aurora, USA., Kanner R; 3 Anvyl LLC, 18092 Sky Park South, Suite F, Irvine, USA., Johnson L; 2 Department of Psychiatry, University of Colorado School of Medicine, Aurora, USA., Hogenkamp D; 1 Department of Pharmacology, School of Medicine, University of California Irvine, Irvine, USA., Harris J; 2 Department of Psychiatry, University of Colorado School of Medicine, Aurora, USA., Tran M; 1 Department of Pharmacology, School of Medicine, University of California Irvine, Irvine, USA., Edmonds SA; 2 Department of Psychiatry, University of Colorado School of Medicine, Aurora, USA., Sauer W; 4 Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, Aurora, USA., Yoshimura R; 1 Department of Pharmacology, School of Medicine, University of California Irvine, Irvine, USA., Johnstone T; 1 Department of Pharmacology, School of Medicine, University of California Irvine, Irvine, USA., Freedman R; 2 Department of Psychiatry, University of Colorado School of Medicine, Aurora, USA. |
| Source: | Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2017 Apr; Vol. 31 (4), pp. 434-441. Date of Electronic Publication: 2017 Feb 15. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1461-7285 |
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| DOI: | 10.1177/0269881117691590 |
