Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

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Title: Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.
Authors: Beckerman P; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bi-Karchin J; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Park AS; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Qiu C; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dummer PD; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA., Soomro I; Division of Nephrology, New York University, New York, New York, USA., Boustany-Kari CM; Department of Cardiometabolic Diseases Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA., Pullen SS; Department of Cardiometabolic Diseases Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA., Miner JH; Division of Nephrology, Washington University School of Medicine, St. Louis, Missouri, USA., Hu CA; Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine and Health Sciences Center, Albuquerque, New Mexico, USA., Rohacs T; Department of Pharmacology, Physiology &Neuroscience, Rutgers-New Jersey Medical School, Newark, New Jersey, USA., Inoue K; Division of Nephrology, Yale University, School of Medicine, New Haven, Connecticut, USA., Ishibe S; Division of Nephrology, Yale University, School of Medicine, New Haven, Connecticut, USA., Saleem MA; Bristol Renal and Children's Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK., Palmer MB; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Cuervo AM; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, New York, USA., Kopp JB; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA., Susztak K; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Source: Nature medicine [Nat Med] 2017 Apr; Vol. 23 (4), pp. 429-438. Date of Electronic Publication: 2017 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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  Data: Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.
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  Data: <searchLink fieldCode="AU" term="%22Beckerman+P%22">Beckerman P</searchLink>; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bi-Karchin+J%22">Bi-Karchin J</searchLink>; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Park+AS%22">Park AS</searchLink>; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Qiu+C%22">Qiu C</searchLink>; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Dummer+PD%22">Dummer PD</searchLink>; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Soomro+I%22">Soomro I</searchLink>; Division of Nephrology, New York University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Boustany-Kari+CM%22">Boustany-Kari CM</searchLink>; Department of Cardiometabolic Diseases Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Pullen+SS%22">Pullen SS</searchLink>; Department of Cardiometabolic Diseases Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Miner+JH%22">Miner JH</searchLink>; Division of Nephrology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Hu+CA%22">Hu CA</searchLink>; Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine and Health Sciences Center, Albuquerque, New Mexico, USA.<br /><searchLink fieldCode="AU" term="%22Rohacs+T%22">Rohacs T</searchLink>; Department of Pharmacology, Physiology &Neuroscience, Rutgers-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Inoue+K%22">Inoue K</searchLink>; Division of Nephrology, Yale University, School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Ishibe+S%22">Ishibe S</searchLink>; Division of Nephrology, Yale University, School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Saleem+MA%22">Saleem MA</searchLink>; Bristol Renal and Children's Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Palmer+MB%22">Palmer MB</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Cuervo+AM%22">Cuervo AM</searchLink>; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kopp+JB%22">Kopp JB</searchLink>; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Susztak+K%22">Susztak K</searchLink>; Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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