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Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.

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Title: Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.
Authors: Hisert KB; 1 Department of Medicine., Heltshe SL; 2 Department of Pediatrics., Pope C; 2 Department of Pediatrics., Jorth P; 3 Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California., Wu X; 4 Department of Genome Sciences., Edwards RM; 5 Department of Radiology, and., Radey M; 6 Department of Microbiology, University of Washington School of Medicine, Seattle, Washington., Accurso FJ; 7 Department of Pediatrics, University of Colorado, Aurora, Colorado., Wolter DJ; 2 Department of Pediatrics., Cooke G; 8 St. Vincent's University Hospital, Dublin, Ireland., Adam RJ; 9 Department of Internal Medicine, University of Iowa, Iowa City, Iowa; and., Carter S; 8 St. Vincent's University Hospital, Dublin, Ireland., Grogan B; 8 St. Vincent's University Hospital, Dublin, Ireland., Launspach JL; 9 Department of Internal Medicine, University of Iowa, Iowa City, Iowa; and., Donnelly SC; 10 Trinity College Dublin, Dublin, Ireland., Gallagher CG; 8 St. Vincent's University Hospital, Dublin, Ireland., Bruce JE; 4 Department of Genome Sciences., Stoltz DA; 9 Department of Internal Medicine, University of Iowa, Iowa City, Iowa; and., Welsh MJ; 9 Department of Internal Medicine, University of Iowa, Iowa City, Iowa; and., Hoffman LR; 2 Department of Pediatrics.; 6 Department of Microbiology, University of Washington School of Medicine, Seattle, Washington., McKone EF; 8 St. Vincent's University Hospital, Dublin, Ireland., Singh PK; 1 Department of Medicine.; 6 Department of Microbiology, University of Washington School of Medicine, Seattle, Washington.
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2017 Jun 15; Vol. 195 (12), pp. 1617-1628.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.
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