Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.

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Title: Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.
Authors: Hernandez LD; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Kroh HK; Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Hsieh E; Merck & Co., Inc., Palo Alto, CA, 94304, USA., Yang X; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Beaumont M; Merck & Co., Inc., Palo Alto, CA, 94304, USA., Sheth PR; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., DiNunzio E; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Rutherford SA; Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Ohi MD; Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Ermakov G; Merck & Co., Inc., Palo Alto, CA, 94304, USA., Xiao L; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Secore S; Merck & Co., Inc., West Point, PA, 19446, USA., Karczewski J; Merck & Co., Inc., West Point, PA, 19446, USA., Racine F; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Mayhood T; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Fischer P; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Sher X; Merck & Co., Inc., Boston, MA, 02115, USA., Gupta P; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Lacy DB; Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Therien AG; Merck & Co., Inc., Kenilworth, NJ, 07033, USA. Electronic address: ATherien@inceptionsci.com.
Source: Journal of molecular biology [J Mol Biol] 2017 Apr 07; Vol. 429 (7), pp. 1030-1044. Date of Electronic Publication: 2017 Feb 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE
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  Data: Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.
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