Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue.
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| Title: | Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue. |
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| Authors: | Addis L; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. laura.addis@kcl.ac.uk.; Neuroscience Discovery, Eli Lilly Research Centre, Windlesham, Surrey, UK. laura.addis@kcl.ac.uk., Virdee JK; Neuroscience Discovery, Eli Lilly Research Centre, Windlesham, Surrey, UK., Vidler LR; Neuroscience Discovery, Eli Lilly Research Centre, Windlesham, Surrey, UK., Collier DA; Neuroscience Discovery, Eli Lilly Research Centre, Windlesham, Surrey, UK., Pal DK; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Ursu D; Neuroscience Discovery, Eli Lilly Research Centre, Windlesham, Surrey, UK. |
| Source: | Scientific reports [Sci Rep] 2017 Feb 27; Vol. 7 (1), pp. 66. Date of Electronic Publication: 2017 Feb 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-017-00115-w |
