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BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.

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Title: BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.
Authors: Hogg SJ; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia., Vervoort SJ; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia., Deswal S; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria., Ott CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Li J; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia., Cluse LA; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia., Beavis PA; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia., Darcy PK; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia., Martin BP; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia., Spencer A; Australian Center for Blood Diseases, Monash University, Melbourne, VIC 3004, Australia., Traunbauer AK; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria., Sadovnik I; Division of Hematology and Hemostaseology, Department of Internal Medicine, Medical University of Vienna, 1090 Wien, Austria., Bauer K; Division of Hematology and Hemostaseology, Department of Internal Medicine, Medical University of Vienna, 1090 Wien, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Wien, Austria., Valent P; Division of Hematology and Hemostaseology, Department of Internal Medicine, Medical University of Vienna, 1090 Wien, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Wien, Austria., Bradner JE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Zuber J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria., Shortt J; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia; Monash Haematology, Monash Health, Clayton, VIC 3168, Australia; School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia. Electronic address: jake.shortt@monashhealth.org., Johnstone RW; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: ricky.johnstone@petermac.org.
Source: Cell reports [Cell Rep] 2017 Feb 28; Vol. 18 (9), pp. 2162-2174.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.
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  Data: <searchLink fieldCode="AU" term="%22Hogg+SJ%22">Hogg SJ</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Vervoort+SJ%22">Vervoort SJ</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Deswal+S%22">Deswal S</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ott+CJ%22">Ott CJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Cluse+LA%22">Cluse LA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Beavis+PA%22">Beavis PA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Darcy+PK%22">Darcy PK</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Martin+BP%22">Martin BP</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Spencer+A%22">Spencer A</searchLink>; Australian Center for Blood Diseases, Monash University, Melbourne, VIC 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Traunbauer+AK%22">Traunbauer AK</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Sadovnik+I%22">Sadovnik I</searchLink>; Division of Hematology and Hemostaseology, Department of Internal Medicine, Medical University of Vienna, 1090 Wien, Austria.<br /><searchLink fieldCode="AU" term="%22Bauer+K%22">Bauer K</searchLink>; Division of Hematology and Hemostaseology, Department of Internal Medicine, Medical University of Vienna, 1090 Wien, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Wien, Austria.<br /><searchLink fieldCode="AU" term="%22Valent+P%22">Valent P</searchLink>; Division of Hematology and Hemostaseology, Department of Internal Medicine, Medical University of Vienna, 1090 Wien, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Wien, Austria.<br /><searchLink fieldCode="AU" term="%22Bradner+JE%22">Bradner JE</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Zuber+J%22">Zuber J</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Shortt+J%22">Shortt J</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia; Monash Haematology, Monash Health, Clayton, VIC 3168, Australia; School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia. Electronic address: jake.shortt@monashhealth.org.<br /><searchLink fieldCode="AU" term="%22Johnstone+RW%22">Johnstone RW</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: ricky.johnstone@petermac.org.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2017 Feb 28; Vol. 18 (9), pp. 2162-2174.
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