Phase II Study of a Radiotherapy Total Dose Increase in Hypoxic Lesions Identified by 18F-Misonidazole PET/CT in Patients with Non-Small Cell Lung Carcinoma (RTEP5 Study).

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Title: Phase II Study of a Radiotherapy Total Dose Increase in Hypoxic Lesions Identified by 18F-Misonidazole PET/CT in Patients with Non-Small Cell Lung Carcinoma (RTEP5 Study).
Authors: Vera P; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France pierre.vera@chb.unicancer.fr., Thureau S; Department of Radiation Oncology and Medical Physics, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, Rouen, France., Chaumet-Riffaud P; Department of Nuclear Medicine, Hôpitaux universitaires Paris Sud Bicêtre AP-HP and University Paris Sud, Paris, France., Modzelewski R; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France., Bohn P; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France., Vermandel M; University Lille, Inserm, CHU Lille, U1189-ONCO-THAI-Image Assisted Laser Therapy for Oncology, Lille, France., Hapdey S; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France., Pallardy A; Department of Nuclear Medicine, Nantes University Hospital, Nantes, France., Mahé MA; Department of Radiation Oncology, Institut de Cancérologie de l'Ouest (ICO)-René Gauducheau, Nantes, France., Lacombe M; Department of Nuclear Medicine, Institut de Cancérologie de l'Ouest (ICO), Nantes, France., Boisselier P; Department of Radiation Oncology, Institut régional du Cancer Montpellier (ICM), Montpellier, France., Guillemard S; Department of Nuclear Medicine, Institut régional du Cancer Montpellier (ICM), Montpellier, France., Olivier P; Department of Nuclear Medicine, Brabois University Hospital, Nancy, France., Beckendorf V; Department of Radiation Oncology, Institut de Cancérologie de Lorraine, Nancy, France., Salem N; Department of Radiation Oncology, Institut Paoli Calmette, Marseille, France., Charrier N; Department of Nuclear Medicine, Institut Paoli Calmette, Marseille, France., Chajon E; Department of Radiation Oncology, Centre regional de lutte contre le cancer de Bretagne Eugène Marquis, Rennes, France., Devillers A; Department of Nuclear Medicine, Centre regional de lutte contre le cancer de Bretagne Eugène Marquis, Rennes, France., Aide N; Nicolas Aide, Nuclear Medicine and TEP Centre, Caen University Hospital and Inserm U1086 ANTICIPE, Caen, France., Danhier S; Department of Radiation Oncology, François Baclesse Cancer Center, Caen, France., Denis F; Department of Radiation Oncology, Institut Inter-Régional de Cancérologie (ILC), Centre Jean Bernard/Clinique Victor Hugo, Le Mans, France., Muratet JP; Department of Nuclear Medicine, Institut Inter-Régional de Cancérologie (ILC), Centre Jean Bernard/Clinique Victor Hugo, Le Mans, France., Martin E; Radiation Oncology, Centre Georges-Francois Leclerc, Dijon, France., Riedinger AB; Department of Nuclear Medicine, Centre Georges Francois Leclerc, Dijon, France., Kolesnikov-Gauthier H; Department of Nuclear Medicine, Oscar Lambret Center, Lille cedex, France., Dansin E; Department of Radiation Oncology, Oscar Lambret Center, Lille cedex, France., Massabeau C; Département de Radiothérapie. Institut Universitaire du Cancer, Toulouse cedex 9, France., Courbon F; Department of Nuclear Medicine, Institut Claudius Regaud, IUCT, Toulouse cedex 9, France., Farcy Jacquet MP; Department of Radiation Oncology, CHU de Nîmes, Institut de cancérologie du Gard, Rue Henri Pujol, Nîmes, France., Kotzki PO; Department of Nuclear Medicine, Institut régional du Cancer Montpellier (ICM), Montpellier, France.; Department of Nuclear Medicine, CHU de Nîmes, Institut de cancérologie du Gard, Nîmes, France., Houzard C; Department of Nuclear Medicine, Hospices Civils de Lyon, Lyon, France., Mornex F; Department of Radiation Oncology, Hospices Civils de Lyon, Lyon, France., Vervueren L; Department of Nuclear Medicine, CHU Angers, France., Paumier A; Department of Radiation Oncology, Institut de Cancérologie de l'Ouest, site Paul Papin, France., Fernandez P; Department of Nuclear Medicine, Hôpital Pellegrin, CHU de Bordeaux, France; and., Salaun M; Normandy University, UNIROUEN, QuantIF-LITIS EA 4108, Rouen University Hospital, Department of Pulmonology-Thoracic Oncology-Respiratory Intensive Care, Rouen, France., Dubray B; Department of Radiation Oncology and Medical Physics, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, Rouen, France.
Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2017 Jul; Vol. 58 (7), pp. 1045-1053. Date of Electronic Publication: 2017 Mar 02.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase II Study of a Radiotherapy Total Dose Increase in Hypoxic Lesions Identified by <superscript>18</superscript>F-Misonidazole PET/CT in Patients with Non-Small Cell Lung Carcinoma (RTEP5 Study).
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  Data: <searchLink fieldCode="AU" term="%22Vera+P%22">Vera P</searchLink>; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France pierre.vera@chb.unicancer.fr.<br /><searchLink fieldCode="AU" term="%22Thureau+S%22">Thureau S</searchLink>; Department of Radiation Oncology and Medical Physics, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Chaumet-Riffaud+P%22">Chaumet-Riffaud P</searchLink>; Department of Nuclear Medicine, Hôpitaux universitaires Paris Sud Bicêtre AP-HP and University Paris Sud, Paris, France.<br /><searchLink fieldCode="AU" term="%22Modzelewski+R%22">Modzelewski R</searchLink>; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Bohn+P%22">Bohn P</searchLink>; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Vermandel+M%22">Vermandel M</searchLink>; University Lille, Inserm, CHU Lille, U1189-ONCO-THAI-Image Assisted Laser Therapy for Oncology, Lille, France.<br /><searchLink fieldCode="AU" term="%22Hapdey+S%22">Hapdey S</searchLink>; Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, University of Rouen, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Pallardy+A%22">Pallardy A</searchLink>; Department of Nuclear Medicine, Nantes University Hospital, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Mahé+MA%22">Mahé MA</searchLink>; Department of Radiation Oncology, Institut de Cancérologie de l'Ouest (ICO)-René Gauducheau, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Lacombe+M%22">Lacombe M</searchLink>; Department of Nuclear Medicine, Institut de Cancérologie de l'Ouest (ICO), Nantes, France.<br /><searchLink fieldCode="AU" term="%22Boisselier+P%22">Boisselier P</searchLink>; Department of Radiation Oncology, Institut régional du Cancer Montpellier (ICM), Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Guillemard+S%22">Guillemard S</searchLink>; Department of Nuclear Medicine, Institut régional du Cancer Montpellier (ICM), Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Olivier+P%22">Olivier P</searchLink>; Department of Nuclear Medicine, Brabois University Hospital, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Beckendorf+V%22">Beckendorf V</searchLink>; Department of Radiation Oncology, Institut de Cancérologie de Lorraine, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Salem+N%22">Salem N</searchLink>; Department of Radiation Oncology, Institut Paoli Calmette, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Charrier+N%22">Charrier N</searchLink>; Department of Nuclear Medicine, Institut Paoli Calmette, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Chajon+E%22">Chajon E</searchLink>; Department of Radiation Oncology, Centre regional de lutte contre le cancer de Bretagne Eugène Marquis, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Devillers+A%22">Devillers A</searchLink>; Department of Nuclear Medicine, Centre regional de lutte contre le cancer de Bretagne Eugène Marquis, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Aide+N%22">Aide N</searchLink>; Nicolas Aide, Nuclear Medicine and TEP Centre, Caen University Hospital and Inserm U1086 ANTICIPE, Caen, France.<br /><searchLink fieldCode="AU" term="%22Danhier+S%22">Danhier S</searchLink>; Department of Radiation Oncology, François Baclesse Cancer Center, Caen, France.<br /><searchLink fieldCode="AU" term="%22Denis+F%22">Denis F</searchLink>; Department of Radiation Oncology, Institut Inter-Régional de Cancérologie (ILC), Centre Jean Bernard/Clinique Victor Hugo, Le Mans, France.<br /><searchLink fieldCode="AU" term="%22Muratet+JP%22">Muratet JP</searchLink>; Department of Nuclear Medicine, Institut Inter-Régional de Cancérologie (ILC), Centre Jean Bernard/Clinique Victor Hugo, Le Mans, France.<br /><searchLink fieldCode="AU" term="%22Martin+E%22">Martin E</searchLink>; Radiation Oncology, Centre Georges-Francois Leclerc, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Riedinger+AB%22">Riedinger AB</searchLink>; Department of Nuclear Medicine, Centre Georges Francois Leclerc, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Kolesnikov-Gauthier+H%22">Kolesnikov-Gauthier H</searchLink>; Department of Nuclear Medicine, Oscar Lambret Center, Lille cedex, France.<br /><searchLink fieldCode="AU" term="%22Dansin+E%22">Dansin E</searchLink>; Department of Radiation Oncology, Oscar Lambret Center, Lille cedex, France.<br /><searchLink fieldCode="AU" term="%22Massabeau+C%22">Massabeau C</searchLink>; Département de Radiothérapie. Institut Universitaire du Cancer, Toulouse cedex 9, France.<br /><searchLink fieldCode="AU" term="%22Courbon+F%22">Courbon F</searchLink>; Department of Nuclear Medicine, Institut Claudius Regaud, IUCT, Toulouse cedex 9, France.<br /><searchLink fieldCode="AU" term="%22Farcy+Jacquet+MP%22">Farcy Jacquet MP</searchLink>; Department of Radiation Oncology, CHU de Nîmes, Institut de cancérologie du Gard, Rue Henri Pujol, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Kotzki+PO%22">Kotzki PO</searchLink>; Department of Nuclear Medicine, Institut régional du Cancer Montpellier (ICM), Montpellier, France.; Department of Nuclear Medicine, CHU de Nîmes, Institut de cancérologie du Gard, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Houzard+C%22">Houzard C</searchLink>; Department of Nuclear Medicine, Hospices Civils de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Mornex+F%22">Mornex F</searchLink>; Department of Radiation Oncology, Hospices Civils de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Vervueren+L%22">Vervueren L</searchLink>; Department of Nuclear Medicine, CHU Angers, France.<br /><searchLink fieldCode="AU" term="%22Paumier+A%22">Paumier A</searchLink>; Department of Radiation Oncology, Institut de Cancérologie de l'Ouest, site Paul Papin, France.<br /><searchLink fieldCode="AU" term="%22Fernandez+P%22">Fernandez P</searchLink>; Department of Nuclear Medicine, Hôpital Pellegrin, CHU de Bordeaux, France; and.<br /><searchLink fieldCode="AU" term="%22Salaun+M%22">Salaun M</searchLink>; Normandy University, UNIROUEN, QuantIF-LITIS EA 4108, Rouen University Hospital, Department of Pulmonology-Thoracic Oncology-Respiratory Intensive Care, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Dubray+B%22">Dubray B</searchLink>; Department of Radiation Oncology and Medical Physics, Henri Becquerel Cancer Center and Rouen University Hospital & QuantIF-LITIS, Rouen, France.
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