Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.
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| Title: | Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction. |
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| Authors: | Blevitt JM; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , La Jolla, California 92121, United States., Hack MD; Lead Discovery, Discovery Sciences, Janssen R&D LLC , La Jolla, California 92121, United States., Herman KL; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , La Jolla, California 92121, United States., Jackson PF; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , La Jolla, California 92121, United States., Krawczuk PJ; Immunology, Janssen R&D LLC , Spring House, Pennsylvania 19477, United States., Lebsack AD; Immunology, Janssen R&D LLC , La Jolla, California 92121, United States., Liu AX; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , Spring House, Pennsylvania 19477, United States., Mirzadegan T; Lead Discovery, Discovery Sciences, Janssen R&D LLC , La Jolla, California 92121, United States., Nelen MI; Lead Discovery, Discovery Sciences, Janssen R&D LLC , Spring House, Pennsylvania 19477, United States., Patrick AN; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , Spring House, Pennsylvania 19477, United States., Steinbacher S; Proteros Biostructures , 82152 Martinsried, Germany., Milla ME; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , La Jolla, California 92121, United States., Lumb KJ; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC , Spring House, Pennsylvania 19477, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2017 Apr 27; Vol. 60 (8), pp. 3511-3517. Date of Electronic Publication: 2017 Mar 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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