Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.

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Title: Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
Authors: Heslop JA; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Kia R; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Pridgeon CS; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Sison-Young RL; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Liloglou T; Department of Molecular and Clinical Cancer Medicine, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Elmasry M; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.; University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL, United Kingdom., Fenwick SW; University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL, United Kingdom., Mills JS; AstraZeneca, Personalised Healthcare and Biomarkers, Alderley Park, Cheshire, SK10 4TG, United Kingdom., Kitteringham NR; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Goldring CE; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom., Park BK; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.
Source: Stem cells translational medicine [Stem Cells Transl Med] 2017 May; Vol. 6 (5), pp. 1321-1331.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print Cited Medium: Print ISSN: 2157-6564 (Print) Linking ISSN: 21576564 NLM ISO Abbreviation: Stem Cells Transl Med Subsets: MEDLINE
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  Data: Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
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  Data: <searchLink fieldCode="AU" term="%22Heslop+JA%22">Heslop JA</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kia+R%22">Kia R</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pridgeon+CS%22">Pridgeon CS</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sison-Young+RL%22">Sison-Young RL</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Liloglou+T%22">Liloglou T</searchLink>; Department of Molecular and Clinical Cancer Medicine, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Elmasry+M%22">Elmasry M</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.; University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fenwick+SW%22">Fenwick SW</searchLink>; University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mills+JS%22">Mills JS</searchLink>; AstraZeneca, Personalised Healthcare and Biomarkers, Alderley Park, Cheshire, SK10 4TG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kitteringham+NR%22">Kitteringham NR</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goldring+CE%22">Goldring CE</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Park+BK%22">Park BK</searchLink>; MRC Centre for Drug Safety Science, Division of Molecular & Clinical Pharmacology, the Institute of Translational Medicine, the University of Liverpool, Liverpool, L69 3GE, United Kingdom.
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