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High efficacy of Sofosbuvir plus Simeprevir in a large cohort of Spanish cirrhotic patients infected with genotypes 1 and 4.

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Title: High efficacy of Sofosbuvir plus Simeprevir in a large cohort of Spanish cirrhotic patients infected with genotypes 1 and 4.
Authors: Mariño Z; Liver Unit, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain., Pascasio-Acevedo JM; Clinical Management Unit of Digestive Diseases, Hospital Universitario Virgen del Rocío, CIBERehd, Sevilla, Spain., Gallego A; Liver Unit, Hospital Santa Creu i Sant Pau, CIBERehd, Barcelona, Spain., Diago M; Digestive Diseases, Hospital Universitario General, Valencia, Spain., Baliellas C; Liver Unit, Hospital Universitari Bellvitge-Instituto de Investigación Biomédica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain., Morillas R; Liver Unit, Hospital Germans Trias i Pujol, CIBERehd, Badalona, Spain., Prieto M; Liver Unit, Hospital Universitario La Fe, Valencia, Spain., Moreno JM; Department of Gastroenterology, Complejo Hospitalario Universitario de Albacete, Albacete, Spain., Sánchez-Antolín G; Department of Gastroenterology, Hospital Universitario Río Hortega, Valladolid, Spain., Vergara M; Liver Unit, Servei d'Aparell Digestiu, Parc Tauli Sabadell Hospital Universitari, Universitat Autónoma Barcelona, Sabadell, Spain., Forné M; Liver Unit, Hospital Universitario Mutua de Terrassa, Terrassa, Spain., Fernández I; Liver Unit, Hospital Universitario 12 de Octubre, Madrid, Spain., Castro MA; Internal Medicine, Grupo de Virología Clínica, Instituto Investigación Biomédica A Coruña (INIBIC)-Hospital Universitario A Coruña, A Coruña, Spain., Pascual S; Liver Unit, Hospital General Universitario Alicante, CIBERehd, Alicante, Spain., Gómez A; Liver Unit, Hospital Universitario Donostia, San Sebastian, Spain., Castells L; Liver Unit, Internal Medicine Department, Hospital Universitari Vall Hebron, CIBERehd, Barcelona, Spain., Montero JL; Liver Unit, Hospital Universitario Reina Sofía, CIBERehd, Córdoba, Spain., Crespo J; Gastroenterology and Hepatology Department, University Hospital Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain., Calleja JL; Liver Unit, Hospital Universitario Puerta de Hierro, Universidad Autonoma de Madrid, CIBERehd, Madrid, Spain., García-Samaniego J; Liver Unit, Hospital Universitario La Paz, CIBERehd, IdiPAZ, Madrid, Spain., Carrión JA; Liver Section, Gastroenterology Department, Hospital del Mar, Universitat Autònoma de Barcelona, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Arencibia AC; Liver Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain., Blasco A; Digestive Diseases, Hospital de Sant Joan Despi Moises Broggi, Barcelona, Spain., López-Núñez C; Digestive Diseases, Hospital Universitari Dr.Josep Trueta, Girona, Spain., Sánchez-Ruano JJ; Digestive Diseases, Hospital Universitario de Toledo, Toledo, Spain., Gea-Rodríguez F; Liver Unit, Hospital Ramón y Cajal, Madrid, Spain., Giráldez Á; Clinical Management Unit of Digestive Diseases, Hospital Universitario Virgen del Rocío, CIBERehd, Sevilla, Spain., Cabezas J; Gastroenterology and Hepatology Department, University Hospital Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain., Hontangas V; Liver Unit, Hospital Universitario La Fe, Valencia, Spain., Torras X; Liver Unit, Hospital Santa Creu i Sant Pau, CIBERehd, Barcelona, Spain., Castellote J; Liver Unit, Hospital Universitari Bellvitge-Instituto de Investigación Biomédica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain., Romero-Gómez M; Liver Unit, Hospital Virgen de Valme, Sevilla, Spain., Turnes J; Digestive Diseases, Complejo Hospitalario Universitario de Pontevedra and IISGS, Pontevedra, Spain., de Artaza T; Digestive Diseases, Hospital Universitario de Toledo, Toledo, Spain., Narváez I; Liver Unit, Hospital Infanta Cristina, Badajoz, Spain., Cuervas-Mons V; Liver Unit, Hospital Universitario Puerta de Hierro, Universidad Autonoma de Madrid, CIBERehd, Madrid, Spain., Forns X; Liver Unit, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.
Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2017 Dec; Vol. 37 (12), pp. 1823-1832. Date of Electronic Publication: 2017 Jun 05.
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High efficacy of Sofosbuvir plus Simeprevir in a large cohort of Spanish cirrhotic patients infected with genotypes 1 and 4.
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  Data: <searchLink fieldCode="AU" term="%22Mariño+Z%22">Mariño Z</searchLink>; Liver Unit, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pascasio-Acevedo+JM%22">Pascasio-Acevedo JM</searchLink>; Clinical Management Unit of Digestive Diseases, Hospital Universitario Virgen del Rocío, CIBERehd, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Gallego+A%22">Gallego A</searchLink>; Liver Unit, Hospital Santa Creu i Sant Pau, CIBERehd, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Diago+M%22">Diago M</searchLink>; Digestive Diseases, Hospital Universitario General, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Baliellas+C%22">Baliellas C</searchLink>; Liver Unit, Hospital Universitari Bellvitge-Instituto de Investigación Biomédica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Morillas+R%22">Morillas R</searchLink>; Liver Unit, Hospital Germans Trias i Pujol, CIBERehd, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Prieto+M%22">Prieto M</searchLink>; Liver Unit, Hospital Universitario La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Moreno+JM%22">Moreno JM</searchLink>; Department of Gastroenterology, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-Antolín+G%22">Sánchez-Antolín G</searchLink>; Department of Gastroenterology, Hospital Universitario Río Hortega, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Vergara+M%22">Vergara M</searchLink>; Liver Unit, Servei d'Aparell Digestiu, Parc Tauli Sabadell Hospital Universitari, Universitat Autónoma Barcelona, Sabadell, Spain.<br /><searchLink fieldCode="AU" term="%22Forné+M%22">Forné M</searchLink>; Liver Unit, Hospital Universitario Mutua de Terrassa, Terrassa, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández+I%22">Fernández I</searchLink>; 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Gastroenterology and Hepatology Department, University Hospital Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Calleja+JL%22">Calleja JL</searchLink>; Liver Unit, Hospital Universitario Puerta de Hierro, Universidad Autonoma de Madrid, CIBERehd, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22García-Samaniego+J%22">García-Samaniego J</searchLink>; Liver Unit, Hospital Universitario La Paz, CIBERehd, IdiPAZ, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Carrión+JA%22">Carrión JA</searchLink>; Liver Section, Gastroenterology Department, Hospital del Mar, Universitat Autònoma de Barcelona, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Arencibia+AC%22">Arencibia AC</searchLink>; Liver Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Blasco+A%22">Blasco A</searchLink>; Digestive Diseases, Hospital de Sant Joan Despi Moises Broggi, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López-Núñez+C%22">López-Núñez C</searchLink>; Digestive Diseases, Hospital Universitari Dr.Josep Trueta, Girona, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-Ruano+JJ%22">Sánchez-Ruano JJ</searchLink>; Digestive Diseases, Hospital Universitario de Toledo, Toledo, Spain.<br /><searchLink fieldCode="AU" term="%22Gea-Rodríguez+F%22">Gea-Rodríguez F</searchLink>; Liver Unit, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Giráldez+Á%22">Giráldez Á</searchLink>; Clinical Management Unit of Digestive Diseases, Hospital Universitario Virgen del Rocío, CIBERehd, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Cabezas+J%22">Cabezas J</searchLink>; Gastroenterology and Hepatology Department, University Hospital Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Hontangas+V%22">Hontangas V</searchLink>; Liver Unit, Hospital Universitario La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Torras+X%22">Torras X</searchLink>; Liver Unit, Hospital Santa Creu i Sant Pau, CIBERehd, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Castellote+J%22">Castellote J</searchLink>; Liver Unit, Hospital Universitari Bellvitge-Instituto de Investigación Biomédica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Romero-Gómez+M%22">Romero-Gómez M</searchLink>; Liver Unit, Hospital Virgen de Valme, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Turnes+J%22">Turnes J</searchLink>; Digestive Diseases, Complejo Hospitalario Universitario de Pontevedra and IISGS, Pontevedra, Spain.<br /><searchLink fieldCode="AU" term="%22de+Artaza+T%22">de Artaza T</searchLink>; Digestive Diseases, Hospital Universitario de Toledo, Toledo, Spain.<br /><searchLink fieldCode="AU" term="%22Narváez+I%22">Narváez I</searchLink>; Liver Unit, Hospital Infanta Cristina, Badajoz, Spain.<br /><searchLink fieldCode="AU" term="%22Cuervas-Mons+V%22">Cuervas-Mons V</searchLink>; 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