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NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.

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Title: NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.
Authors: Griesinger AM; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Witt DA; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Grob ST; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Georgio Westover SR; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Donson AM; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Sanford B; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Mulcahy Levy JM; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Wong R; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Moreira DC; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., DeSisto JA; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Balakrishnan I; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Hoffman LM; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Handler MH; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Jones KL; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Venkataraman S; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado., Foreman NK; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.
Source: Neuro-oncology [Neuro Oncol] 2017 Oct 01; Vol. 19 (10), pp. 1350-1360.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.
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  Data: <searchLink fieldCode="AU" term="%22Griesinger+AM%22">Griesinger AM</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Witt+DA%22">Witt DA</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Grob+ST%22">Grob ST</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Georgio+Westover+SR%22">Georgio Westover SR</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Donson+AM%22">Donson AM</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Sanford+B%22">Sanford B</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Mulcahy+Levy+JM%22">Mulcahy Levy JM</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Wong+R%22">Wong R</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Moreira+DC%22">Moreira DC</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22DeSisto+JA%22">DeSisto JA</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Balakrishnan+I%22">Balakrishnan I</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Hoffman+LM%22">Hoffman LM</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Handler+MH%22">Handler MH</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Jones+KL%22">Jones KL</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Vibhakar+R%22">Vibhakar R</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Venkataraman+S%22">Venkataraman S</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Foreman+NK%22">Foreman NK</searchLink>; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.
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