View in EDS PDF Full Text

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.

Saved in:
Bibliographic Details
Title: Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.
Authors: Steinman JB; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States., Santarossa CC; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States., Miller RM; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States., Yu LS; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States., Serpinskaya AS; Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States., Furukawa H; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Morimoto S; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Tanaka Y; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Nishitani M; Pharmaceutical Research Division, Takeda Pharmaceuticals Ltd, Kanagawa, Japan., Asano M; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Zalyte R; Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom., Ondrus AE; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States., Johnson AG; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States., Ye F; Department of Molecular and Cellular Physiology, Stanford University, Stanford, United States., Nachury MV; Department of Molecular and Cellular Physiology, Stanford University, Stanford, United States., Fukase Y; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Aso K; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Foley MA; Tri-Institutitional Therapeutics Discovery Institute, New York, United States., Gelfand VI; Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States., Chen JK; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States., Carter AP; Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom., Kapoor TM; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States.
Source: ELife [Elife] 2017 May 19; Vol. 6. Date of Electronic Publication: 2017 May 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 28524820
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Steinman+JB%22">Steinman JB</searchLink>; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States.<br /><searchLink fieldCode="AU" term="%22Santarossa+CC%22">Santarossa CC</searchLink>; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States.<br /><searchLink fieldCode="AU" term="%22Miller+RM%22">Miller RM</searchLink>; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States.<br /><searchLink fieldCode="AU" term="%22Yu+LS%22">Yu LS</searchLink>; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States.<br /><searchLink fieldCode="AU" term="%22Serpinskaya+AS%22">Serpinskaya AS</searchLink>; Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States.<br /><searchLink fieldCode="AU" term="%22Furukawa+H%22">Furukawa H</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Morimoto+S%22">Morimoto S</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Nishitani+M%22">Nishitani M</searchLink>; Pharmaceutical Research Division, Takeda Pharmaceuticals Ltd, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+M%22">Asano M</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Zalyte+R%22">Zalyte R</searchLink>; Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ondrus+AE%22">Ondrus AE</searchLink>; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Johnson+AG%22">Johnson AG</searchLink>; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.<br /><searchLink fieldCode="AU" term="%22Ye+F%22">Ye F</searchLink>; Department of Molecular and Cellular Physiology, Stanford University, Stanford, United States.<br /><searchLink fieldCode="AU" term="%22Nachury+MV%22">Nachury MV</searchLink>; Department of Molecular and Cellular Physiology, Stanford University, Stanford, United States.<br /><searchLink fieldCode="AU" term="%22Fukase+Y%22">Fukase Y</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Aso+K%22">Aso K</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Foley+MA%22">Foley MA</searchLink>; Tri-Institutitional Therapeutics Discovery Institute, New York, United States.<br /><searchLink fieldCode="AU" term="%22Gelfand+VI%22">Gelfand VI</searchLink>; Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States.<br /><searchLink fieldCode="AU" term="%22Chen+JK%22">Chen JK</searchLink>; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.<br /><searchLink fieldCode="AU" term="%22Carter+AP%22">Carter AP</searchLink>; Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kapoor+TM%22">Kapoor TM</searchLink>; Laboratory of Chemistry and Cell Biology, Rockefeller University, New York, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2017 May 19; Vol. 6. <i>Date of Electronic Publication: </i>2017 May 19.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22eLife+Sciences+Publications%2C+Ltd%22">eLife Sciences Publications, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101579614 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-084X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222050084X%22">2050084X </searchLink><i>NLM ISO Abbreviation: </i>Elife <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=28524820
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.7554/eLife.25174
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Steinman JB
      – PersonEntity:
          Name:
            NameFull: Santarossa CC
      – PersonEntity:
          Name:
            NameFull: Miller RM
      – PersonEntity:
          Name:
            NameFull: Yu LS
      – PersonEntity:
          Name:
            NameFull: Serpinskaya AS
      – PersonEntity:
          Name:
            NameFull: Furukawa H
      – PersonEntity:
          Name:
            NameFull: Morimoto S
      – PersonEntity:
          Name:
            NameFull: Tanaka Y
      – PersonEntity:
          Name:
            NameFull: Nishitani M
      – PersonEntity:
          Name:
            NameFull: Asano M
      – PersonEntity:
          Name:
            NameFull: Zalyte R
      – PersonEntity:
          Name:
            NameFull: Ondrus AE
      – PersonEntity:
          Name:
            NameFull: Johnson AG
      – PersonEntity:
          Name:
            NameFull: Ye F
      – PersonEntity:
          Name:
            NameFull: Nachury MV
      – PersonEntity:
          Name:
            NameFull: Fukase Y
      – PersonEntity:
          Name:
            NameFull: Aso K
      – PersonEntity:
          Name:
            NameFull: Foley MA
      – PersonEntity:
          Name:
            NameFull: Gelfand VI
      – PersonEntity:
          Name:
            NameFull: Chen JK
      – PersonEntity:
          Name:
            NameFull: Carter AP
      – PersonEntity:
          Name:
            NameFull: Kapoor TM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 19
              M: 05
              Text: 2017 May 19
              Type: published
              Y: 2017
          Identifiers:
            – Type: issn-electronic
              Value: 2050-084X
          Numbering:
            – Type: volume
              Value: 6
          Titles:
            – TitleFull: ELife
              Type: main
ResultId 1