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γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.

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Title: γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
Authors: Ran Y; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA yran@ufl.edu tgolde@ufl.edu., Hossain F; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Pannuti A; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Lessard CB; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Ladd GZ; College of Pharmacy, University of Florida, Gainesville, FL, USA., Jung JI; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Minter LM; Department of Veterinary and Animal Sciences and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA, USA., Osborne BA; Department of Veterinary and Animal Sciences and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA, USA., Miele L; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Golde TE; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA yran@ufl.edu tgolde@ufl.edu.
Source: EMBO molecular medicine [EMBO Mol Med] 2017 Jul; Vol. 9 (7), pp. 950-966.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
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  Data: <searchLink fieldCode="AU" term="%22Ran+Y%22">Ran Y</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA yran@ufl.edu tgolde@ufl.edu.<br /><searchLink fieldCode="AU" term="%22Hossain+F%22">Hossain F</searchLink>; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Pannuti+A%22">Pannuti A</searchLink>; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Lessard+CB%22">Lessard CB</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ladd+GZ%22">Ladd GZ</searchLink>; College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Jung+JI%22">Jung JI</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Minter+LM%22">Minter LM</searchLink>; Department of Veterinary and Animal Sciences and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Osborne+BA%22">Osborne BA</searchLink>; Department of Veterinary and Animal Sciences and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Miele+L%22">Miele L</searchLink>; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Golde+TE%22">Golde TE</searchLink>; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA yran@ufl.edu tgolde@ufl.edu.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2017 Jul; Vol. 9 (7), pp. 950-966.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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              Text: 2017 Jul
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