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Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.

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Title: Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.
Authors: Mimura Y; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan. mimuray66@outlook.jp., Katoh T; Laboratory of Molecular Biology and Bioresponse, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Oiwake-Cho, Sakyo-Ku, Kyoto, 606-8502, Japan., Saldova R; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland., O'Flaherty R; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland., Izumi T; Center for Regenerative Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Japan., Mimura-Kimura Y; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan., Utsunomiya T; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan., Mizukami Y; Center for Gene Research, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan., Yamamoto K; Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, 1-308 Suematsu, Nonoichi, Ishikawa, 921-8836, Japan., Matsumoto T; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan., Rudd PM; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.
Source: Protein & cell [Protein Cell] 2018 Jan; Vol. 9 (1), pp. 47-62. Date of Electronic Publication: 2017 Jun 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 101532368 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1674-8018 (Electronic) Linking ISSN: 1674800X NLM ISO Abbreviation: Protein Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Mimura+Y%22">Mimura Y</searchLink>; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan. mimuray66@outlook.jp.<br /><searchLink fieldCode="AU" term="%22Katoh+T%22">Katoh T</searchLink>; Laboratory of Molecular Biology and Bioresponse, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Oiwake-Cho, Sakyo-Ku, Kyoto, 606-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Saldova+R%22">Saldova R</searchLink>; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Flaherty+R%22">O'Flaherty R</searchLink>; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.<br /><searchLink fieldCode="AU" term="%22Izumi+T%22">Izumi T</searchLink>; Center for Regenerative Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Japan.<br /><searchLink fieldCode="AU" term="%22Mimura-Kimura+Y%22">Mimura-Kimura Y</searchLink>; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan.<br /><searchLink fieldCode="AU" term="%22Utsunomiya+T%22">Utsunomiya T</searchLink>; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan.<br /><searchLink fieldCode="AU" term="%22Mizukami+Y%22">Mizukami Y</searchLink>; Center for Gene Research, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+K%22">Yamamoto K</searchLink>; Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, 1-308 Suematsu, Nonoichi, Ishikawa, 921-8836, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+T%22">Matsumoto T</searchLink>; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan.<br /><searchLink fieldCode="AU" term="%22Rudd+PM%22">Rudd PM</searchLink>; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.
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  Data: <searchLink fieldCode="JN" term="%22101532368%22">Protein & cell</searchLink> [Protein Cell] 2018 Jan; Vol. 9 (1), pp. 47-62. <i>Date of Electronic Publication: </i>2017 Jun 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101532368 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1674-8018 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221674800X%22">1674800X </searchLink><i>NLM ISO Abbreviation: </i>Protein Cell <i>Subsets: </i>MEDLINE
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              Text: 2018 Jan
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