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Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury.

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Title: Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury.
Authors: Weaver RJ; a Research & Biopharmacy, Institut de Recherches Internationales Servier , Suresnes , France., Betts C; b Pathology Sciences, Drug Safety and Metabolism , AstraZeneca R&D , Cambridge , UK., Blomme EAG; c Preclinical Safety , AbbVie , North Chicago , USA., Gerets HHJ; d Non Clinical Development, Chemin du Foriest , UCB BioPharma SPRL , Braine L'Alleud , Belgium., Gjervig Jensen K; e Drug ADME Research, H. Lundbeck A/S , 9 Ottiliavej , Valby , Denmark., Hewitt PG; f Non-Clinical Development, Merck KGaA , Darmstadt , Germany., Juhila S; g In Vitro Biology , Orion Pharma , Espoo , Finland., Labbe G; h Investigative Toxicology, Preclinical Safety , Sanofi R&D , Paris , France., Liguori MJ; c Preclinical Safety , AbbVie , North Chicago , USA., Mesens N; i Preclinical Development & Safety, Janssen (Pharmaceutical Companies of Johnson & Johnson) Turnhoutseweg 30 , Beerse , Belgium., Ogese MO; j Pathology Sciences, Drug Safety and Metabolism , AstraZeneca R&D , Cambridge , UK., Persson M; k Innovative Medicines and Early Clinical Development, Drug Safety and Metabolism, Discovery Safety , AstraZeneca R&D , Mölndal , Sweden., Snoeys J; l Pharmacokinetics Dynamics & Metabolism, Janssen (Pharmaceutical Companies of Johnson & Johnson) Turnhoutseweg 30 , Beerse , Belgium., Stevens JL; m Dept of Toxicology , Lilly Research Laboratories, Eli Lilly and Company , Indianapolis , Indiana , USA., Walker T; n Investigative Safety & Drug Metabolism , GlaxoSmithKline, David Jack Centre for Research and Development , Ware , Herts , Hertfordshire, UK., Park BK; o Institute of Translational Medicine , University of Liverpool , Liverpool , UK.
Source: Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2017 Jul; Vol. 13 (7), pp. 767-782. Date of Electronic Publication: 2017 Jun 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7607 (Electronic) Linking ISSN: 17425255 NLM ISO Abbreviation: Expert Opin Drug Metab Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury.
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  Data: <searchLink fieldCode="AU" term="%22Weaver+RJ%22">Weaver RJ</searchLink>; a Research & Biopharmacy, Institut de Recherches Internationales Servier , Suresnes , France.<br /><searchLink fieldCode="AU" term="%22Betts+C%22">Betts C</searchLink>; b Pathology Sciences, Drug Safety and Metabolism , AstraZeneca R&D , Cambridge , UK.<br /><searchLink fieldCode="AU" term="%22Blomme+EAG%22">Blomme EAG</searchLink>; c Preclinical Safety , AbbVie , North Chicago , USA.<br /><searchLink fieldCode="AU" term="%22Gerets+HHJ%22">Gerets HHJ</searchLink>; d Non Clinical Development, Chemin du Foriest , UCB BioPharma SPRL , Braine L'Alleud , Belgium.<br /><searchLink fieldCode="AU" term="%22Gjervig+Jensen+K%22">Gjervig Jensen K</searchLink>; e Drug ADME Research, H. Lundbeck A/S , 9 Ottiliavej , Valby , Denmark.<br /><searchLink fieldCode="AU" term="%22Hewitt+PG%22">Hewitt PG</searchLink>; f Non-Clinical Development, Merck KGaA , Darmstadt , Germany.<br /><searchLink fieldCode="AU" term="%22Juhila+S%22">Juhila S</searchLink>; g In Vitro Biology , Orion Pharma , Espoo , Finland.<br /><searchLink fieldCode="AU" term="%22Labbe+G%22">Labbe G</searchLink>; h Investigative Toxicology, Preclinical Safety , Sanofi R&D , Paris , France.<br /><searchLink fieldCode="AU" term="%22Liguori+MJ%22">Liguori MJ</searchLink>; c Preclinical Safety , AbbVie , North Chicago , USA.<br /><searchLink fieldCode="AU" term="%22Mesens+N%22">Mesens N</searchLink>; i Preclinical Development & Safety, Janssen (Pharmaceutical Companies of Johnson & Johnson) Turnhoutseweg 30 , Beerse , Belgium.<br /><searchLink fieldCode="AU" term="%22Ogese+MO%22">Ogese MO</searchLink>; j Pathology Sciences, Drug Safety and Metabolism , AstraZeneca R&D , Cambridge , UK.<br /><searchLink fieldCode="AU" term="%22Persson+M%22">Persson M</searchLink>; k Innovative Medicines and Early Clinical Development, Drug Safety and Metabolism, Discovery Safety , AstraZeneca R&D , Mölndal , Sweden.<br /><searchLink fieldCode="AU" term="%22Snoeys+J%22">Snoeys J</searchLink>; l Pharmacokinetics Dynamics & Metabolism, Janssen (Pharmaceutical Companies of Johnson & Johnson) Turnhoutseweg 30 , Beerse , Belgium.<br /><searchLink fieldCode="AU" term="%22Stevens+JL%22">Stevens JL</searchLink>; m Dept of Toxicology , Lilly Research Laboratories, Eli Lilly and Company , Indianapolis , Indiana , USA.<br /><searchLink fieldCode="AU" term="%22Walker+T%22">Walker T</searchLink>; n Investigative Safety & Drug Metabolism , GlaxoSmithKline, David Jack Centre for Research and Development , Ware , Herts , Hertfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Park+BK%22">Park BK</searchLink>; o Institute of Translational Medicine , University of Liverpool , Liverpool , UK.
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        Value: 10.1080/17425255.2017.1341489
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        Text: English
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              Text: 2017 Jul
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