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Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits.

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Title: Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits.
Authors: Hammerschlag AR; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Stringer S; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., de Leeuw CA; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Sniekers S; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Taskesen E; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands., Watanabe K; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Blanken TF; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.; Department of Integrative Neurophysiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, the Netherlands., Dekker K; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands., Te Lindert BHW; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands., Wassing R; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands., Jonsdottir I; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Thorleifsson G; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland., Stefansson H; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland., Gislason T; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Respiratory Medicine and Sleep, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Schormair B; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Wellmann J; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Winkelmann J; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany.; Neurologische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universität München, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Stefansson K; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Oexle K; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany., Van Someren EJW; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.; Department of Integrative Neurophysiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, the Netherlands., Posthuma D; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.
Source: Nature genetics [Nat Genet] 2017 Nov; Vol. 49 (11), pp. 1584-1592. Date of Electronic Publication: 2017 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hammerschlag+AR%22">Hammerschlag AR</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Stringer+S%22">Stringer S</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Leeuw+CA%22">de Leeuw CA</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sniekers+S%22">Sniekers S</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Taskesen+E%22">Taskesen E</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Watanabe+K%22">Watanabe K</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Blanken+TF%22">Blanken TF</searchLink>; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.; Department of Integrative Neurophysiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dekker+K%22">Dekker K</searchLink>; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Te+Lindert+BHW%22">Te Lindert BHW</searchLink>; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wassing+R%22">Wassing R</searchLink>; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Jonsdottir+I%22">Jonsdottir I</searchLink>; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Thorleifsson+G%22">Thorleifsson G</searchLink>; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Stefansson+H%22">Stefansson H</searchLink>; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Gislason+T%22">Gislason T</searchLink>; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Respiratory Medicine and Sleep, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Berger+K%22">Berger K</searchLink>; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schormair+B%22">Schormair B</searchLink>; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wellmann+J%22">Wellmann J</searchLink>; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Winkelmann+J%22">Winkelmann J</searchLink>; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany.; Neurologische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universität München, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; deCODE Genetics, Amgen, Inc., Reykjavík, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Oexle+K%22">Oexle K</searchLink>; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Van+Someren+EJW%22">Van Someren EJW</searchLink>; Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands.; Department of Integrative Neurophysiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Posthuma+D%22">Posthuma D</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2017 Nov; Vol. 49 (11), pp. 1584-1592. <i>Date of Electronic Publication: </i>2017 Jun 12.
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