PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.

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Title: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
Authors: Thorpe LM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.; Program in Virology, Harvard Medical School, Boston, MA 02115., Spangle JM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115., Ohlson CE; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115., Cheng H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115., Roberts TM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115., Cantley LC; Weill Cornell Medical Center, New York, NY 10065 lcantley@med.cornell.edu jean_zhao@dfci.harvard.edu., Zhao JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; lcantley@med.cornell.edu jean_zhao@dfci.harvard.edu.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Jul 03; Vol. 114 (27), pp. 7095-7100. Date of Electronic Publication: 2017 Jun 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
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  Data: <searchLink fieldCode="AU" term="%22Thorpe+LM%22">Thorpe LM</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.; Program in Virology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Spangle+JM%22">Spangle JM</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Ohlson+CE%22">Ohlson CE</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Cheng+H%22">Cheng H</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Roberts+TM%22">Roberts TM</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Cantley+LC%22">Cantley LC</searchLink>; Weill Cornell Medical Center, New York, NY 10065 lcantley@med.cornell.edu jean_zhao@dfci.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Zhao+JJ%22">Zhao JJ</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; lcantley@med.cornell.edu jean_zhao@dfci.harvard.edu.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2017 Jul 03; Vol. 114 (27), pp. 7095-7100. <i>Date of Electronic Publication: </i>2017 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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        Value: 10.1073/pnas.1704706114
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        Text: English
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      – TitleFull: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
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              Text: 2017 Jul 03
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