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Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.

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Title: Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.
Authors: Doveston RG; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands., Kuusk A; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Andrei SA; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands., Leysen S; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands., Cao Q; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Waltham, MA, USA., Castaldi MP; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Waltham, MA, USA., Hendricks A; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Waltham, MA, USA., Brunsveld L; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands., Chen H; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Boyd H; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Ottmann C; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.; Department of Chemistry, University of Duisburg-Essen, Germany.
Source: FEBS letters [FEBS Lett] 2017 Aug; Vol. 591 (16), pp. 2449-2457. Date of Electronic Publication: 2017 Aug 06.
Publication Type: Letter; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.
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  Data: <searchLink fieldCode="AU" term="%22Doveston+RG%22">Doveston RG</searchLink>; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuusk+A%22">Kuusk A</searchLink>; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Andrei+SA%22">Andrei SA</searchLink>; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Leysen+S%22">Leysen S</searchLink>; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cao+Q%22">Cao Q</searchLink>; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Castaldi+MP%22">Castaldi MP</searchLink>; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hendricks+A%22">Hendricks A</searchLink>; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Brunsveld+L%22">Brunsveld L</searchLink>; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Boyd+H%22">Boyd H</searchLink>; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Ottmann+C%22">Ottmann C</searchLink>; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.; Department of Chemistry, University of Duisburg-Essen, Germany.
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  Data: <searchLink fieldCode="JN" term="%220155157%22">FEBS letters</searchLink> [FEBS Lett] 2017 Aug; Vol. 591 (16), pp. 2449-2457. <i>Date of Electronic Publication: </i>2017 Aug 06.
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