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Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.

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Title: Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.
Authors: Behjati S; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.; Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.; Corpus Christi College, Cambridge CB2 1RH, UK., Tarpey PS; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Haase K; The Francis Crick Institute, London NW1 1AT, UK., Ye H; Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK., Young MD; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Alexandrov LB; Theoretical Biology and Biophysics (T-6), Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA., Farndon SJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK., Collord G; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Wedge DC; Oxford Big Data Institute and Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK., Martincorena I; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Cooke SL; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Davies H; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Mifsud W; UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK., Lidgren M; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Martin S; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Latimer C; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Maddison M; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Butler AP; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Teague JW; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Pillay N; Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK.; University College London Cancer Institute, Huntley Street, London WC1E 6BT, UK., Shlien A; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., McDermott U; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Futreal PA; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.; Department of Genomic Medicine, MD Anderson Cancer Center, University of Texas, Houston, Texas 77030, USA., Baumhoer D; Bone Tumour Reference Centre, Institute of Pathology, University Hospital Basel, University of Basel, Basel 4031, Switzerland., Zaikova O; Oslo University Hospital, Oslo 0379, Norway., Bjerkehagen B; Oslo University Hospital, Oslo 0379, Norway., Myklebost O; Oslo University Hospital, Oslo 0379, Norway.; University of Bergen, Bergen 5020, Norway., Amary MF; Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK., Tirabosco R; Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK., Van Loo P; The Francis Crick Institute, London NW1 1AT, UK.; Department of Human Genetics, University of Leuven, Leuven B-3000, Belgium., Stratton MR; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK., Flanagan AM; Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK.; University College London Cancer Institute, Huntley Street, London WC1E 6BT, UK., Campbell PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.; Department of Haematology, University of Cambridge, Hills Road, Cambridge CB2 2XY, UK.
Source: Nature communications [Nat Commun] 2017 Jun 23; Vol. 8, pp. 15936. Date of Electronic Publication: 2017 Jun 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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