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Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.

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Title: Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.
Authors: Quévillon Huberdeau M; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada., Zeitler DM; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany., Hauptmann J; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany., Bruckmann A; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany., Fressigné L; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada., Danner J; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany., Piquet S; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada., Strieder N; Department of Statistical Bioinformatics, University of Regensburg, Regensburg, Germany., Engelmann JC; Department of Statistical Bioinformatics, University of Regensburg, Regensburg, Germany., Jannot G; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada., Deutzmann R; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany., Simard MJ; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada martin.simard@crchudequebec.ulaval.ca gunter.meister@ur.de.; Laval University Cancer Research Centre, Quebec City, Québec, Canada., Meister G; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany martin.simard@crchudequebec.ulaval.ca gunter.meister@ur.de.
Source: The EMBO journal [EMBO J] 2017 Jul 14; Vol. 36 (14), pp. 2088-2106. Date of Electronic Publication: 2017 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Quévillon+Huberdeau+M%22">Quévillon Huberdeau M</searchLink>; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Zeitler+DM%22">Zeitler DM</searchLink>; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hauptmann+J%22">Hauptmann J</searchLink>; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bruckmann+A%22">Bruckmann A</searchLink>; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fressigné+L%22">Fressigné L</searchLink>; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Danner+J%22">Danner J</searchLink>; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Piquet+S%22">Piquet S</searchLink>; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Strieder+N%22">Strieder N</searchLink>; Department of Statistical Bioinformatics, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Engelmann+JC%22">Engelmann JC</searchLink>; Department of Statistical Bioinformatics, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jannot+G%22">Jannot G</searchLink>; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada.; Laval University Cancer Research Centre, Quebec City, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Deutzmann+R%22">Deutzmann R</searchLink>; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Simard+MJ%22">Simard MJ</searchLink>; St-Patrick Research Group in Basic Oncology, Centre Hospitalier Universitaire de Québec-Université Laval Research Centre (L'Hôtel-Dieu de Québec), Quebec City, Québec, Canada martin.simard@crchudequebec.ulaval.ca gunter.meister@ur.de.; Laval University Cancer Research Centre, Quebec City, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Meister+G%22">Meister G</searchLink>; Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany martin.simard@crchudequebec.ulaval.ca gunter.meister@ur.de.
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